Results 111 to 120 of about 6,588,200 (233)

Anion‐Selective Channels Formed by Synthetic 13‐Mer Chimeric α ‐Peptide‐Oligourea Foldamers

Chemistry – A European Journal, EarlyView.
Synthetic 13‐mer α‐peptide‐oligourea chimeric foldamers self‐assemble into supramolecular ion channels, demonstrating high ion transport activity with distinct anion selectivity in lipid membranes. This study supports the design of bioinspired functional foldamer‐based channels for synthetic ion transport applications.
Chiranjit Dutta, Dandan Su, Pannaga Krishnamurthy, Zhaoxing Li, Jianwei Li, Morgane Pasco, Min Luo, Mihail Barboiu, Gilles Guichard, R. Manjunatha Kini, Prakash Kumar   +10 more
wiley   +1 more source

Association between lifestyle habits and central sensitization in community-dwelling older adults in Japan: a cross-sectional analysis from the Otassha study

BMC Geriatrics
Background Disruptions in daily lifestyle habits are associated with various health issues, including chronic pain. Central sensitization, characterized by heightened responsiveness of the central nervous system, plays a key role in pain perception ...
Takeaki Takeuchi, Kazuaki Hashimoto, Kazushige Ihara, Shuichi Obuchi, Hirohiko Hirano, Yoshinori Fujiwara, Hisashi Kawai, Hiroyuki Sasai, Masahiro Hashizume   +8 more
doaj   +1 more source

Multimodal Fluorescent MOF@BODIPY Platform: Bridging Sensing and Mechanistic Insight

Chemistry – A European Journal, EarlyView.
ABSTRACT Hybrid metal–organic frameworks (MOFs) that integrate organic chromophores constitute powerful platforms for optical sensing by combining structural order with tunable photophysics. Incorporating photoresponsive chromophores into MOFs enables sensitive probing of guest–framework interactions through well‐defined luminescent signatures. Herein,
Alejandro Cortés‐Villena, Paula Rodrigo‐Martínez, José A. Sáez, Pablo Gaviña, Emilio Pardo, Raquel E. Galian, Sergio Armenta, Héctor Martínez‐Pérez‐Cejuela, José Manuel Herrero‐Martínez   +8 more
wiley   +1 more source

Linking central sensitization to multisystemic manifestations in hypermobile Ehlers-Danlos syndrome

Frontiers in Pain Research
Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) are complex multisystemic conditions frequently associated with chronic pain.
Ana Paula Montemayor Zarazúa, César Vidal Elizondo Solis, Camila Ayala García, Diego Jesús Pacheco Estrella, Octavio Ilizaliturri Guerra, Ana Cecilia Arana Guajardo, Emma Purón Gonzalez, Karina Silva Luna, Luis Iván Lozano Plata, Mario Ramon García Pompermayer, Mario Alberto Garza Elizondo   +10 more
doaj   +1 more source

Cellular Membrane‐Targeted Europium(III) Probe for Selective and Time‐Resolved Detection of Peroxynitrite

Chemistry – A European Journal, EarlyView.
We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb, Rebecca Tiffany, Karolis Norvaisa, Hennie Valkenier, Lea Miebach, Sander Bekeschus, Stephen J. Butler   +6 more
wiley   +1 more source

Reference ranges and influencing factors of pressure pain threshold in Chinese patients with knee osteoarthritis

Annals of Medicine
Background Pressure pain threshold (PPT) is a reliable objective measure of pain sensitization; however, standardized region-specific reference data for Chinese patients with knee osteoarthritis (KOA) remain scarce.
Zhiheng Hu, Xiaofeng Chang, Shuxin Yao, Feng Ye, Chao Xu, Jianbing Ma   +5 more
doaj   +1 more source

Formation of Lanthanide Luminescent Aggregates With RNA Using Tripodal Europium [Eu(III)] BTA Self‐Assembled Complexes

Chemistry – A European Journal, EarlyView.
The two Eu(III) complexes of 1.Eu and 2.Eu, that were formed in situ, were used to bind to yeast RNA and A10 (RNA) in a buffered pH 7 solution. The interaction gave rise to changes in the lanthanide‐centered emission because of direct binding of these complexes, which resulted in aggregation of the RNA, as demonstrated using phase‐contrast and atomic ...
Tómas A. Gudmundsson, Changzhuang Bai, Grace E. Maynard, Pall Thordarson, Thorfinnur Gunnlaugsson   +4 more
wiley   +1 more source

[Therapy of disorders with central pain sensitization.]

, 2009
Previous somatic pain experience (priming), psychobiographic imprinting (pain proneness), and stress (action proneness) are key to an enhanced centralised pain response. This centralised pain response clinically manifests itself in pain sensitization and
Egloff, N, Egle, U T, von Känel, R
core  

Designing a Triplet 2‐Formylphenylnitrene With Fast Tunneling Reactivity

Chemistry – A European Journal, EarlyView.
A 3‐CF3 substituent accelerates tunneling in triplet 2‐formylphenylnitrene, making its reactivity in cryogenic matrices too fast for conventional IR spectroscopic detection. Bringing this chemistry to low‐temperature solutions allows suppression of intrinsic nitrene dimerization through faster cyclization, which even outcompetes the 1,4‐H shift ...
Sofia Braz, Cláudio M. Nunes, Simon Schlosser, Peter R. Schreiner, Rui Fausto   +4 more
wiley   +1 more source

Temporomandibular disorders and Central Sensitization Inventory: an exploratory study

, 2019
Objectives: Temporomandibular disorders (TMD) can be associated with impaired pain mechanisms often defined as Central Sensitization(CS)(1–3). The Central Sensitization Inventory (CSI) was designed to identify andquantify key symptoms associated with CS ...
Denis, Corentin, Roussel, Nathalie, Pitance, Laurent, European congress of Manual therapy 2019 (ECMT)", Antwerp, Cayrol, Timothée   +4 more
core