Results 151 to 160 of about 6,588,200 (233)

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

CROSS CULTURAL ADAPTATION, RELIABILITY AND VALIDITY OF THE FRENCH VERSION OF THE CENTRAL SENSITIZATION INVENTORY

, 2016
Background: Central sensitization has been proposed as a pathophysiological pain mechanism in which central nervous system neurons become hyperexcitable, resulting in hypersensitivity to both noxious and non-noxious stimuli.
Dethier, Vincent, Eeckhout, Coralie, International Federation of Orthopaedic Manipulative Physical Therapists, Lannoy, Bérangère, Berquin, Anne, Robertson, Johanna, Meuus, Marie, Pitance, Laurent, Meeus, Mira, Roussel, Nathalie, Piraux, Elise   +10 more
core  

Heavy‐Metal‐Free Colloidal Quantum Dots for Photocatalysis

Small, EarlyView.
Heavy‐metal‐free colloidal quantum dots provide sustainable photocatalytic platforms by combining tunable band structures, strong light absorption, and programmable surfaces/interfaces. This Review highlights how core/shell engineering, alloying, defect regulation, ligand design, and hybrid‐interface construction direct charge separation and ...
Xintong Xu, Ge Yang, Qin Li, Dechao Chen
wiley   +1 more source

Goffman's Tempting the Devil in Stigma: A Close Rereading of Goffman's “Subversive” Construct of “the Normals” Versus “the Stigmatized”

Symbolic Interaction, EarlyView.
This article engages in a close rereading of Stigma, relating it to Goffman's biography as a person who faced stigma. Exploring his biography helps us to recognize the ways Goffman applies stigma strategies in how he represents himself as the author in Stigma.
Thaddeus Müller
wiley   +1 more source

PPM1G‒MET axis sustains AKT signaling to drive Twist‐associated EMT and drug resistance in hepatocellular carcinoma

VIEW, EarlyView.
Hepatocellular carcinoma (HCC) is frequently resistant to targeted therapies. We identify protein phosphatase Mg2+/Mn2+‐dependent 1G (PPM1G) as a key phosphatase that stabilizes mesenchymal‐epithelial transition factor (MET) by inhibiting its ubiquitination, thereby sustaining protein kinase B (AKT) signaling and promoting Twist‐mediated epithelial ...
Weixun Wu, Songbin Lin, Cong Zhou, Jinwu Hu, Kun Liu, Yongfeng Xu, Zhenbin Ding, Mengting Luo, Bo Hu   +8 more
wiley   +1 more source

When Thriving for More Collapses the System: The Academic Reproduction of Uncaring Structures

British Journal of Management, EarlyView.
Abstract This essay argues that the widening gap between aspirational aims and visionary orientations and the prevailing practices in neoliberal academia stems from deeper, historically rooted, market‐based logics shaping our institutions, increasingly governed by economic values and academic subjectivities therein.
Lara Pecis, Florian Bauer
wiley   +1 more source

UNPACKING THE SUSTAINABILITY FIX: Governance Mechanisms in Urban Redevelopment Across Central and Eastern Europe

International Journal of Urban and Regional Research, EarlyView.
Abstract This article examines how sustainability is mobilized as a governance strategy in large‐scale urban redevelopment. Focusing on the RIVUS Mall project in Cluj‐Napoca, alongside comparative cases from Bratislava and Gdańsk, it traces how environmental objectives are translated into institutional practices, planning rationales, and financial ...
MIHAI IACOB
wiley   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

From allostasis to addiction: Cortisol dysregulation, daily stress and relations with 9‐year alcohol and substance use disorder severity in community adults

Addiction, EarlyView.
Abstract Background and aims Diurnal cortisol dysregulation and daily stressor severity may jointly forecast long‐term alcohol use disorder (AUD) and substance use disorder (SUD) severity, yet most evidence is cross‐sectional and relies on single cortisol indices.
Nur Hani Zainal, Natalia Van Doren
wiley   +1 more source

The Evolution of Sesame Seed Allergy Over Time

Allergy, EarlyView.
This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong, George Du Toit, Henry T. Bahnson, Ronald van Ree, Suzana Radulovic, Serge A. Versteeg, Joanna Craven, Matthew Kwok, Zainab Jama, Helen A. Brough, Kirsty Logan, Michael R. Perkin, Carsten Flohr, Alexandra F. Santos, Gideon Lack   +14 more
wiley   +1 more source