Results 31 to 40 of about 200,011 (267)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Design and application of a fully automatic throat swab cartridge exit device for nucleic acid detection (一种用于核酸检测的全自动咽拭子弹出装置的设计与应用)

中西医结合护理, 2023
This paper introduced the design and application of a fully automatic throat swab cartridge exit device for nucleic acid detection. The aim of this throat swab cartridge exit device is to improve the nucleic acid detection efficiency and reduce the risk ...
ZHU Kunkun (朱坤坤), XU Yuanle (许远乐), WANG Yuena (王岳娜), WU Bo (武博)   +3 more
doaj   +1 more source

A coordinated scheduling of delivery and inventory in a multi-location hospital supplied with a central pharmacy [PDF]

Logistics Research, 2016
In today’s manufacturing outlook, coordinated scheduling of delivery and inventory represents a leading leverage to enhance the competitiveness of firms which aims to address the new challenge coming from scheduling problems. Though in the last decades this kind of issue has been extensively approached in the literature, a set of constraints and ...
Hammoudan, Zakaria, Grunder, Olivier, Boudouh, Toufik, ElMoudni, Abdellah   +3 more
openaire   +4 more sources

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

The effects of perfusion device technology in the cleaning of luminal instruments

Sterile Supply
ObjectiveTo observe the application effect of perfusion device technology in the cleaning of luminal instruments.MethodsA total of 400 of lumen surgical instruments received from the disinfection supply center of our hospital from April to October 2023 ...
Meifeng Cao, Chunxia Qian
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

H-type hypertension is a risk factor for chronic total coronary artery occlusion: a cross-sectional study from southwest China

BMC Cardiovascular Disorders, 2023
Background Chronic total coronary occlusion (CTO) is serious and the "last bastion" of percutaneous coronary intervention. Hypertension and hyperhomocysteinemia (HHCY) are synergistic and significantly increase cardiovascular event risk. The relationship
Kaiyong Xiao, Zhe Xv, Yuling Xv, Jianping Wang, Lian Xiao, Zhou Kang, Jianhui Zhu, Zhongwei He, Guan Huang   +8 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Dual-Robot Collaborative Automated Sterile Pack Storage System for the Central Sterile Supply Department: Design and Performance Validation

Sterile Supply
ObjectiveThis study aimed to address the low efficiency of sterile item storage management in the Central Sterile Supply Department (CSSD) and to construct and validate the actual performance of a dual-robot collaborative scheduling system.MethodsA ...
Jin Wang, Xinxin Yang, Lingyan He, Yabin Lai   +3 more
doaj   +1 more source