Results 81 to 90 of about 2,465 (291)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Comparative study of receiver performance in solar power tower [PDF]

open access: yes, 2017
114 p. : ill. ; 30 cmAmong all Concentrating Solar Power technologies available for power generation, the solar power tower, also known as central receiver system, is attracting a lot of interest day to day.
Yamani, Noureddine
core  

User's manual for DELSOL2: a computer code for calculating the optical performance and optimal system design for solar-thermal central-receiver plants [PDF]

open access: yes, 1981
DELSOL2 is a revised and substantially extended version of the DELSOL computer program for calculating collector field performance and layout, and optimal system design for solar thermal central receiver plants.
Fish, M. J., Dellin, T. A., Yang, C. L.
core   +1 more source

Modeling and Energetic Analysis of a Supercritical Carbon Dioxide sCO2 Recompression-Organic Rankine Cycle Integrated to a Central Tower Receiver

open access: yesSolarPACES Conference Proceedings
This study presents a comprehensive thermodynamic model and energetic analysis of a hybrid Concentrated Solar Power (CSP) system incorporating a supercritical carbon dioxide (sCO2) Brayton cycle and an Organic Rankine Cycle (ORC).
Jesus Alberto Moctezuma-Hernandez   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Small-Scale Solar Central Receiver System Design and Analysis [PDF]

open access: yes, 2012
This thesis develops an analytical model of a small-scale solar central receiver power plant located at the California Polytechnic State University in San Luis Obispo, California at 35.28° N, 120.66° W. The model is used to analyze typical energy output
Murray, Daniel
core   +2 more sources

Inverse Heat Transfer Analysis for Estimating Heat Flux in Solar Tower Receivers

open access: yesSolarPACES Conference Proceedings
Solar power tower plants are utilized to harness solar radiation for large-scale electricity generation. The concentrated solar radiation is absorbed by the central receiver to heat a transfer fluid, which is typically a mixture of 60% sodium nitrate ...
Vahid Safari   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Novel analysis of second law and irreversibility for a solar power plant using heliostat field and molten salt

open access: yesEnergy Science & Engineering, 2020
Nowadays, the low efficiency of solar energy power plant systems brings about uneconomical performance and high‐cost uncompetitive industries compared with the traditional fossil fuel ones.
Mohammad Hossein Zolfagharnasab   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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