Results 31 to 40 of about 79,538 (262)

Shape Memory Polymer‐Based Flexible Pressure Sensor for Real‐Time Venous Thrombosis Monitoring

Advanced Materials Interfaces, EarlyView.
A shape‐memory tubular flexible pressure sensor with a 100‐mesh microstructured SMP‐PLA/MWCNTs sensing layer was developed for PICC‐mounted monitoring of thrombosis‐related pressure changes. The sensor combines high sensitivity (204 kPa−1), a fast response time (28 ms), and conformal catheter fixation and was validated by hydrostatic and ex vivo ...
Yi Chen, Mengtao Huang, Ang Wang, Linsen Tang, Mengting He, Xuejin Li, Shaoxing Qu, Zongrong Wang   +7 more
wiley   +1 more source

Outcome-based simulation training for ultrasound-guided central venous catheter placement: clinical impact on preventing mechanical complications

BMC Medical Education
Background Central venous catheter placement has been associated with mechanical complications, some of which can be life-threatening. Recent studies have shown that simulation-based education on ultrasound-guided central venous catheter placement ...
Joho Tokumine, Tomoko Yorozu, Kiyoshi Moriyama, Teruko Suzuki, Chikako Okada   +4 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Genotypic study documents divergence in the pathogenesis of bloodstream infection related central venous catheters in neonates

Brazilian Journal of Infectious Diseases, 2014
Objective: To investigate the pathogenesis of bloodstream infection by Staphylococcus epidermidis, using the molecular epidemiology, in high-risk neonates. Methods: We conducted a prospective study of a cohort of neonates with bloodstream infection using
Cristiane Silveira Brito, Rosineide Marques Ribas, Daiane Silva Resende, Denise Von Dolinger de Brito, Vânia Olivetti Steffen Abdallah, Kátia Regina Netto dos Santos, Fernanda Sampaio Cavalcante, Pricilla Dias Moura de Matos, Paulo P. Gontijo Filho   +8 more
doaj   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Thrombolytic therapy for central venous catheter occlusion

Haematologica, 2012
Background Long-term central venous catheters have improved the quality of care for patients with chronic illnesses, but are complicated by obstructions which can result in delay of treatment or catheter removal.Design and Methods This paper reviews ...
Jacquelyn L. Baskin, Ulrike Reiss, Judith A. Wilimas, Monika L. Metzger, Raul C. Ribeiro, Ching-Hon Pui, Scott C. Howard   +6 more
doaj   +1 more source

Optimization of Magnetic Milli‐Spinner for Robotic Endovascular Intervention

Advanced Robotics Research, EarlyView.
This work presents the design optimization of a multifunctional magnetic milli‐spinner for high‐speed propulsion and efficient clot debulking. The optimized design achieves an ultrafast swimming velocity of 55 cm/s (≈175 body lengths/s) in saline water, enabling stable upstream swimming against strong physiological flows and establishing magnetic milli‐
Lu Lu, Luca Higgins, Jack Bernardo, Ruike Renee Zhao   +3 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Umbilical venous catheter and peripherally inserted central catheter malposition and tip migration in neonates: A mixed methods cost analysis

International Journal of Nursing Studies Advances
Background: Hospitalized neonates require reliable vascular access for life-saving care. The costs associated with their clinical management, and which aspects of care these costs are attributable to, is not well-known.
Arun M Jones, Suzanna Mongan, Amanda Ullman, Deanne August, Elizabeth Sharpe, Angela A Alderman, Darcy Doellman, Caitlin Anders, Kacey Wiseman, Cheryl Gillette, Hansoo Kim, Joshua Byrnes   +11 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source