Results 191 to 200 of about 6,186,932 (245)

Responsive nanoheterojunctions for built‐in electric field‐promoted cascade tumor targeting and cuproptosis‐based therapy

Responsive Materials, EarlyView.
Nanoheterojunctions have been synthesized as responsive biomaterials for cascade targeting of tumor cells and mitochondria, ROS‐mediated apoptosis and Cu‐promoted cuproptosis. And drug‐device‐field integration as an advanced paradigm of tumor treatment was employed for photo‐triggered tumor cell elimination in vitro and lesion eradication in vivo ...
Zhe Liu, Yandai Lin, Xuehui Li, Fengqi Xuan   +3 more
wiley   +1 more source

Intelligent Continuum Micromachines in Complex Confined Spaces

SmartBot, EarlyView.
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai, Yunyue Yang, Shuxing Xu, Jinbo Hu, Jiliang Wang, Zhehao Gan, Wei Tang, Tian‐Yun Huang   +7 more
wiley   +1 more source

PDA‐Engineered 3D‐Printed Polymer–ZrO2 Hybrid Scaffolds Enabling Enhanced Radiopacity, Photothermal Therapy, and Cell Migration Modulation

Small, EarlyView.
A multifunctional 3D‐printed polymer–ZrO2 scaffold is developed to provide intrinsic radiopacity, photothermal responsiveness, and surface bioactivity. Reinforcement with ZrO2 enables real‐time x‐ray visibility and mechanical robustness, while a polydopamine coating facilitates near‐infrared‐triggered drug release and modulates cell migration, thereby ...
Sumin Kang, Yun‐Jin Jeong, Seokjae Kim, Van Du Nguyen, Songah Jeong, Juyeong Jo, Arunkumar Shanmugasundaram, Jin Uk Jeong, Dong‐Weon Lee, Eunpyo Choi, Hyungwoo Kim   +10 more
wiley   +1 more source

Hydrogen‐bond‐mediated retention of a phenolic SNAP analogue in polyvinyl alcohol/PEG hydrogels for sustained nitric oxide release and antibacterial activity

Smart Molecules, EarlyView.
A hydrogen‐bond‐donating NO donor was designed to interact specifically with the hydrogel network, thereby minimizing donor leakage and achieving prolonged NO release. Abstract Nitric oxide (NO)‐releasing materials have attracted considerable interest for their potential in diverse biomedical applications.
Yixin Zhu, Peixuan Wu, Shuting Zhang, Congjun Xu, Guanghua Xia, Jiangli Fan, Nicola E. Brasch, Yang Zhou, Yuanyuan Liu   +8 more
wiley   +1 more source

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

SusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang, Jiahao Liang, Xijing Yang, Xin Song, Yujie Xiao, Xiran Zhou, Hongyu Xiang, Shujing Wang, Shengjun Cheng, Xianda Liu, Yu Chen, Weifeng Zhao, Changsheng Zhao   +12 more
wiley   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

UroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega, Mariela R. Martinez, Steven Friedman, Tehilla Adams, Jordan L. Mendelson, William Nguyen, Jordan S. Gitlin   +6 more
wiley   +1 more source

[MEP-43] Methemoglobinemia After Central Venous Catheterization Due to Local Anesthesia with Prilocaine: A Case Report. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Yıldız A, Ertuğrul M, Kurdal AT, Amanvermez Şenarslan D.   +3 more
europepmc   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

A Dedicated Device for Inside-Out Central Venous Catheterization. [PDF]

Tex Heart Inst J
Benfor B, Peden EK.
europepmc   +1 more source

Assessing veterinary students’ attitudes towards pain in cattle before and after final‐year clinical training

Veterinary Record, EarlyView.
Abstract Background Cattle only show subtle signs of pain, making pain assessment difficult. The approach to pain and the use of analgesics depend on the treating person's experience and opinions. Methods Bavarian veterinary students were asked to answer two identical questionnaires before and after 12 weeks of clinical training in a ruminant clinic. A
Theresa Tschoner, Kristina R. Mueller, Yury Zablotski, Melanie Feist   +3 more
wiley   +1 more source