Results 191 to 200 of about 260,131 (298)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Central venous pressure as a method of optimising atrio-ventricular delay after cardiac surgery. [PDF]

PLoS One
Tindale A, Cretu I, Gomez N, Haynes R, Meng H, Mason MJ, Francis DP.   +6 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Controlled low central venous pressure in laparoscopic left hemihepatectomy for left hepatolithiasis with prior upper abdominal surgery: A retrospective cohort study. [PDF]

Medicine (Baltimore)
He D, Fan Y, Liu J, Chen H, Hu W, Pan W, Ran L, Fang L, Huang J.   +8 more
europepmc   +1 more source

Venous-right atrial bypass for superior vena cava thrombosis during orthotopic liver transplantation [PDF]

, 1997
Antonio D. Pinna, Atsushi Sugitani, Foley, John J. Fung, Kang, LeVeen, Luigi Marongiu, Moskovitz, Patricia Thistlethwaite, Satoru Todo, Shaw, Smadja, Thomas E. Starzl, Tzakis, Yoogoo Kang   +14 more
core   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Resuscitation of patients with septic shock: please "mind the gap"! [PDF]

, 2013
Cecconi, M, Pinsky, MR, Vallet, B
core   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Influence of Increased Intra-Abdominal Pressure on the Validity of Ultrasound-Derived Inferior Vena Cava Measurements for Estimating Central Venous Pressure. [PDF]

J Clin Med
Rora Bertović M, Trkulja V, Ćurčić Karabaić E, Šundalić S, Bielen L, Ivičić T, Radonić R.   +6 more
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source