Results 151 to 160 of about 3,045,859 (239)

Resilience and evolutionary insights in PPI networks: comparative analysis of node resilience and centrality measures. [PDF]

Front Genet
Zhang J.
europepmc   +1 more source

Beyond non-backtracking: non-cycling network centrality measures. [PDF]

Proc Math Phys Eng Sci, 2020
Arrigo F, Higham DJ, Noferini V.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Correction: On the role of diffusion dynamics on community-aware centrality measures. [PDF]

PLoS One
Rajeh S, Cherifi H.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Critical node detection in temporal social networks, based on global and semi-local centrality measures. [PDF]

PLoS One
Farahi Z, Abedian R, Rocha LEC, Kamandi A.   +3 more
europepmc   +1 more source

MultiCens: Multilayer network centrality measures to uncover molecular mediators of tissue-tissue communication

, 2022
Kumar T, Sethuraman R, Mitra S, Ravindran B, Narayanan M.   +4 more
europepmc   +1 more source

RETRACTED ARTICLE: An Intelligent Centrality Measures for Influential Node Detection in COVID-19 Environment.

Wirel Pers Commun, 2022
Jeyasudha J, Usha G.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source