Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Impact of seed node position on network robustness under localized attacks. [PDF]
Chujyo M, Liu S, Toriumi F.
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
National identity as both cure and curse: The effects of three facets of national identification on post-traumatic stress (PTS) symptoms in wartime Ukraine. [PDF]
Bilewicz M +4 more
europepmc +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
RinPy, a Python Package for Residue Interaction Network Model to Analyze Protein Structures and Predict Ligand Binding Sites. [PDF]
Sarica Z, Sungur FA, Kurkcuoglu O.
europepmc +1 more source
Non-linear failure patterns in urban road networks exposed to flooding. [PDF]
Karagiorgos K +4 more
europepmc +1 more source
An Evaluation Method for Influential Nodes Based on Multi-Attribute Neighbor Contributions in Complex Networks. [PDF]
Zhao N +5 more
europepmc +1 more source
Graph convolutional network for modeling corridor-based urban transformation: Revealing spatial coherence in land-use change in Erbil. [PDF]
Amen MA, Nia HA, Aziz AM.
europepmc +1 more source

