Results 91 to 100 of about 578,628 (285)

The relationship between psychological resilience and emotion regulation in Chinese adolescents: a psychological network analysis

Frontiers in Psychology
BackgroundAlthough psychological resilience and emotion regulation are crucial factors influencing mental health, network analysis studies examining their interrelationships in adolescents are scarce.MethodsA cross-sectional study was conducted in ...
Yingjun Xiang, Chengjun Lu, Chengjun Lu, Shujuan Wei, Jiejing Hao, Jiejing Hao, Xiaoya Sun, Ziyu Chen   +7 more
doaj   +1 more source

Vasectomy Discussions in South Korea: Central Themes and Public Interest on Question-and-Answer Social Platforms [PDF]

International Neurourology Journal
Purpose The purpose of this paper is to explore public perceptions and key issues related to vasectomy in South Korea. In particular, this paper seeks to analyze how vasectomy is discussed on question-and-answer (Q&A) social platforms including NAVER ...
Ho Seong Kang, Jung Yoon Kim
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Global Research Landscape and Intellectual Structure of Boron Neutron Capture Therapy Research: A Review Based on Scientometric Tools [PDF]

International Journal of Information Science and Management
Boron Neutron Capture Therapy (BNCT) is a non-invasive therapeutic technique for treating invasive malignant tumors. A tremendous amount of research is published in this area every year, and it needs to be analyzed and evaluated to measure the growth and
Elmira Janavi, Maryamm Emami, Manoj Kumar Verma   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A network analysis approach to strengthening agroecology collaborations: a methodological study of network organizations

Discover Agriculture
This paper proposes a methodological framework for diagnosing and strengthening collaboration within agroecology networks through the application of social network analysis (SNA). While civil society organizations are playing an increasingly central role
Charles L. Tumuhe, Denis Katusiime, David Ssekamatte, Ronald Byaruhanga, Valentina Nyame   +4 more
doaj   +1 more source

VINCENT - Visualization of Network Centralities [PDF]

Proceedings of the International Conference on Computer Graphics Theory and Applications, 2012
Andreas Kerren, Harald Köstinger, Björn Zimmer   +2 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source