Results 31 to 40 of about 761,074 (275)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

A Survey on Parameter Server Architecture: Approaches for Optimizing Distributed Centralized Learning

open access: yesIEEE Access
Deep learning has emerged as a cornerstone technology across various domains, from image classification to natural language processing. However, the computational and data demands of training large-scale neural networks pose significant challenges ...
Nikodimos Provatas   +2 more
doaj   +1 more source

Centralized vs Decentralized Multi-Agent Guesswork

open access: yes, 2017
We study a notion of guesswork, where multiple agents intend to launch a coordinated brute-force attack to find a single binary secret string, and each agent has access to side information generated through either a BEC or a BSC.
Beirami, Ahmad   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Synthetic Neuraminidase Vaccine Induces Cross-Species and Multi-Subtype Protection

open access: yesVaccines
The genetic diversity of influenza A virus is a major obstacle that makes vaccine effectiveness variable and unpredictable. Objectives: Current vaccines induce strain-specific immunity that oftentimes fail to protect against divergent strains.
Matthew J. Pekarek   +7 more
doaj   +1 more source

Decentralized Implementation of Centralized Controllers for Interconnected Systems [PDF]

open access: yes, 2010
Given a centralized controller associated with a linear time-invariant interconnected system, this paper is concerned with designing a parameterized decentralized controller such that the state and input of the system under the obtained decentralized ...
Lavaei, Javad
core  

Centralized Coded Caching with User Cooperation

open access: yes, 2019
In this paper, we consider the coded-caching broadcast network with user cooperation, where a server connects with multiple users and the users can cooperate with each other through a cooperation network.
Chen, Jiahui   +4 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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