Results 21 to 30 of about 2,842,218 (178)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Poisson centralizer of the trace [PDF]
, 2018 The Poisson centralizer of the trace element Σi xi,i is determined in the coordinate ring of SLn endowed with the Poisson structure obtained as the semiclassical limit of its quantized coordinate ring.
Mészáros, Szabolcs
core +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Partitioned groups and the additive structure of centralizer near-rings [PDF]
Proceedings of the Edinburgh Mathematical Society, 1984 If G is a finite group and A is a group of automorphisms of G, the “centralizer” nearring C(A, G) consists of the identity-preserving maps from G to itself which commute with the action of A. The main concern of this paper will be with the additive structur of C(A, G) in the case that this near-ring is semisimple.
openaire +1 more source
Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir +9 more
wiley +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
Advanced Functional Materials, EarlyView.This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
On Zero-Symmetric Left Centrally Prime Near-Rings [PDF]
Kirkuk University Journal-Scientific Studies, 2007 Our aim in this paper is: to give some properties of zero-symmetric left centrally prime near-rings, then looking for those conditions which make zero-symmetric left centrally prime near-rings abelian, so that several conditions are given under which zero-symmetric left centrally prime near-rings become abelian.
openaire +2 more sources
Digitally Printed Eco‐Friendly Electronic Devices
Advanced Functional Materials, EarlyView.Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair +5 more
wiley +1 more source