Results 191 to 200 of about 93,365 (307)

PiggyBac-mediated transgenesis and CRISPR-Cas9 knockout in the greater wax moth, Galleria mellonella. [PDF]

Lab Anim (NY)
Pearce JC, Campbell JS, Prior JL, Titball RW, Wakefield JG.   +4 more
europepmc   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Case Report: Post-stroke hemorrhagic infarction in a status epilepticus Beagle dog. [PDF]

Front Vet Sci
Joshi NM, Jayaprakash R, Panchal PP, Patel UP, Ranvir R, Patel S, Sundar R, Jain MR.   +7 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

RasGRP1 signaling is required for Vγ2+ thymocyte c-Maf expression and γδT17 lineage programming. [PDF]

J Immunol
Joannou K, Golec DP, Azad AK, Henao Caviedes LM, May JF, Kelly RG, Baldwin TA.   +6 more
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Balloon dilatation for bronchoscope delivery: first-in-human trial of a novel technique for peripheral lung field access. [PDF]

Thorax
Miyake K, Oki M, Suzuki H, Saka H, Sasada S, Okamoto N, Imabayashi T, Kogure Y, Shiroyama T, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.   +12 more
europepmc   +1 more source

The settlement of Europe: a centre-periphery logic

, 2010
Compte tenu des différences de densité de population en Europe, le peuplement de ce continent respecte, grosso modo, une logique centre-périphérie, avec au centre, une dorsale européenne dense, puis une périphérie limitrophe moins dense et, ensuite, une densité encore plus faible au delà de cette périphérie limitrophe.
openaire   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

DANEELpath open source digital analysis tools for histopathological research in neuroblastoma models. [PDF]

Sci Rep
Vieco-Martí I, López-Carrasco A, Navarro S, Granados-Aparici S, Noguera R.   +4 more
europepmc   +1 more source