Results 181 to 190 of about 4,506,201 (347)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Centres culturals, centres multimèdia = Centres culturels, centres multimédia

Quaderns d'arquitectura i urbanisme, 1996
Perrault, Dominique, Suzuki, Akira
openaire   +1 more source

Flood risk management centred on clusters of territorial vulnerability [PDF]

, 2016
Florent Renard
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Postoperative Surgical Site Infections in the Department of General Surgery of a Tertiary Care Centre: A Descriptive Cross-sectional Study

, 2022
Pradeep Ghimire, Binod Bade Shrestha, Om Bahadur Karki, Bishowdeep Timilsina, Ananda Neupane, Aprajita Bhandari   +5 more
openalex   +2 more sources

Home-based versus centre-based cardiac rehabilitation.

Cochrane Database of Systematic Reviews, 2017
Lindsey Anderson, Georgina A Sharp, Rebecca J Norton, H. Dalal, S. Dean, K. Jolly, Aynsley Cowie, A. Zawada, R. Taylor   +8 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Balloon plus oxytocin or oral misoprostol for labour induction in prelabour rupture of membranes (PROM): protocol for a randomised controlled trial (RUBAPRO2). [PDF]

BMJ Open
Rouzaire M, Triolaire A, Vayssière C, Sentilhes L, Barjat T, Luton D, Groupe de Recherche en Obstetrique et Gynécologie (GROG) Investigators, Davoust E, Cabrespine A, Pereira B, Gallot D.   +10 more
europepmc   +1 more source

Trauma centres

Journal of British Surgery, 1993
openaire   +2 more sources

Species are not most abundant in the centre of their geographic range or climatic niche.

Ecology Letters, 2017
T. Dallas, Robin R. Decker, A. Hastings
semanticscholar   +1 more source