Results 51 to 60 of about 544,958 (312)
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Object-centric Process Predictive Analytics [PDF]
arXiv, 2022 Object-centric processes (a.k.a. Artifact-centric processes) are implementations of a paradigm where an instance of one process is not executed in isolation but interacts with other instances of the same or other processes. Interactions take place through bridging events where instances exchange data.
arxiv
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
, 2009 We analyze high resolution, N-body hydrodynamical simulations of fiducial galaxy clusters to probe tidal stripping of the dark matter subhalos. These simulations include a prescription for star formation allowing us to track the fate of the stellar ...
Limousin, Marceau +3 more
core +1 more source
Speech Detection Task Against Asian Hate: BERT the Central, While Data-Centric Studies the Crucial [PDF]
arXiv, 2022 With the COVID-19 pandemic continuing, hatred against Asians is intensifying in countries outside Asia, especially among the Chinese. There is an urgent need to detect and prevent hate speech towards Asians effectively. In this work, we first create COVID-HATE-2022, an annotated dataset including 2,025 annotated tweets fetched in early February 2022 ...
arxiv
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Human-centric Image Cropping with Partition-aware and Content-preserving Features [PDF]
arXiv, 2022 Image cropping aims to find visually appealing crops in an image, which is an important yet challenging task. In this paper, we consider a specific and practical application: human-centric image cropping, which focuses on the depiction of a person. To this end, we propose a human-centric image cropping method with two novel feature designs for the ...
arxiv
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Vision-Centric BEV Perception: A Survey [PDF]
arXiv, 2022 In recent years, vision-centric Bird's Eye View (BEV) perception has garnered significant interest from both industry and academia due to its inherent advantages, such as providing an intuitive representation of the world and being conducive to data fusion.
arxiv
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source