Results 61 to 70 of about 270,309 (306)

Retinal changes and cardiac biomarker assessment in relation to chronic kidney disease: a single centre study [PDF]

open access: gold, 2023
Ruslinda Mustafar   +9 more
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Comparative evaluation of condylar position in symptomatic (TMJ dysfunction) and asymptomatic individuals

open access: yesIndian Journal of Dental Research, 2012
Context: The etiopathogenesis of temporomandibular joint (TMJ) disorders has been attributed to multiple factors and, while the importance of centric relation (CR) has been acknowledged in dental literature, the role of condylar position and CR-CO (CO ...
Soumya Padala   +2 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Assessment of the clinical procedures used for determination of vertical dimension of occlusion and centric relation in edentulous patients [PDF]

open access: yesRomanian Journal of Stomatology
Background and aim. This study aims to explore the most widely used methods for managing patients who are completely edentulous to determine the intermaxillary relations, also known as the centric relation and vertical dimension of occlusion.
Cecilia Bacali   +3 more
doaj   +1 more source

Evaluation of the quantitative accuracy of 3D reconstruction of edentulous jaw models with jaw relation based on reference point system alignment. [PDF]

open access: yesPLoS ONE, 2015
OBJECTIVES:To apply contact measurement and reference point system (RPS) alignment techniques to establish a method for 3D reconstruction of the edentulous jaw models with centric relation and to quantitatively evaluate its accuracy.
Weiwei Li   +4 more
doaj   +1 more source

Water resources management versus the world

open access: yesAIMS Geosciences, 2021
Effective water resources management and water availability are under threat from multiple sources, including population growth, continuing urbanisation, and climate change.
John Greenway
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Centric relation: concepts revision and recording techniques. Part I [PDF]

open access: yes, 2008
La relación céntrica ha sido objeto de disparidad de criterios en la odontología durante más de un siglo. A lo largo de este trabajo, vamos a exponer diferentes métodos usados tanto para obtener el registro, como para comprobar su certeza y corroborar la
Arroyo Cruz, Gema   +5 more
core   +1 more source

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