Results 81 to 90 of about 554,752 (351)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

CLINICAL OUTCOMES OF LAYERED LITHIUM DISILICATE RESTORATIONS: A RETROSPECTIVE ANALYSIS

Romanian Journal of Oral Rehabilitation
This study investigates the survival rates and failure modes of layered lithium disilicate restorations with feldspathic ceramic layering, observing a total of 546 restorations across 62 patients, evenly distributed by gender (31 males and 31 females ...
Dan Lolos, Roxana Buzatu, Roxana Oancea, Stefania Dinu, Anca Tudor, Sorin Gheorghe Mihali   +5 more
doaj   +1 more source

The Effect of a Condylar Repositioning Plate on Condylar Position and Relapse in Two-Jaw Surgery

Archives of Plastic Surgery, 2017
Background Numerous condylar repositioning methods have been reported. However, most of them are 2-dimensional or are complex procedures that require a longer operation time and a highly trained surgeon.
Gyu Sik Jung, Taek Kyun Kim, Jeong Woo Lee, Jung Dug Yang, Ho Yun Chung, Byung Chae Cho, Kang Young Choi   +6 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Sabina Leonelli: What constitutes trustworthy data changes across time and space [PDF]

, 2015
The next installment of the Philosophy of Data Science series is with Sabina Leonelli, Principal Investigator of the ERC project, The Epistemology of Data-Intensive Science.
Carrigan, Mark, Leonelli, Sabina
core  

Object-centric Process Predictive Analytics [PDF]

arXiv, 2022
Object-centric processes (a.k.a. Artifact-centric processes) are implementations of a paradigm where an instance of one process is not executed in isolation but interacts with other instances of the same or other processes. Interactions take place through bridging events where instances exchange data.
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Editorial : towards an enhancement of knowledge generation in marketing by contributions from non-western contexts [PDF]

, 2014
This editorial paper highlights the significance of scholarly contributions from non-western contexts to business and management studies in general and marketing in particular.
Jafari, Aliakbar
core  

Speech Detection Task Against Asian Hate: BERT the Central, While Data-Centric Studies the Crucial [PDF]

arXiv, 2022
With the COVID-19 pandemic continuing, hatred against Asians is intensifying in countries outside Asia, especially among the Chinese. There is an urgent need to detect and prevent hate speech towards Asians effectively. In this work, we first create COVID-HATE-2022, an annotated dataset including 2,025 annotated tweets fetched in early February 2022 ...
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source