Results 201 to 210 of about 28,564 (295)

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

3D‐Printed Crosslinked Nanocellulose‐MXene Hydrogels and Aerogels with High Strength and Conductivity

open access: yesSmall, EarlyView.
This study presents a robust strategy for 3D printing conductive, mechanically resilient MXene–CNF composite structures using a single‐step freeze‐induced crosslinking method. The printed architectures remain stable in both wet and dry states, exhibit high electrical conductivity and mechanical strength, and demonstrate practical application in fully ...
Nuzhet Inci Kilic   +5 more
wiley   +1 more source

Effect of Coating Thickness on a Solid-Liquid Two-Phase Flow Centrifugal Pump under Water Medium [PDF]

open access: diamond, 2019
Kaikai Luo   +5 more
openalex   +1 more source

Scale‐Specific Viscoelastic Characterization of Hydrogels: Integrated AFM and Finite Element Modeling

open access: yesSmall, EarlyView.
An integrated multiscale approach reveals distinct viscoelastic responses of hydrogels across length scales. Combining AFM‐based nanoindentation, finite element modeling, and a novel analytical framework, this study enables accurate, scale‐specific mechanical characterization to guide the design of advanced biomaterials. Abstract Viscoelastic hydrogels
Nicole Fertala   +7 more
wiley   +1 more source

Thermo‐Chemically Modified Silk Scaffolds Reveal Niche‐Driven Regulation of Hematopoiesis and Fibrosis

open access: yesSmall, EarlyView.
We introduce a versatile 3D platform that recreates key physical and biological features of the human bone marrow. By integrating tunable silk biomaterials, stromal cells, and human hematopoietic progenitors, the model captures both healthy and diseased microenvironments, analysis of blood formation, and its disruption in pathological conditions ...
Christian A. Di Buduo   +13 more
wiley   +1 more source

Cardenolide‐Engineered Extracellular Vesicles Augment Drug Uptake and Cytotoxicity in Non‐small Cell Lung Cancer Cells

open access: yesSmall Methods, EarlyView.
Cardenolide‐functionalized extracellular vesicles enable targeted delivery of the chemotherapeutic doxorubicin to A549 lung cancer cells by binding Na+/K+‐ATPase, which is overexpressed in these cells. Surface‐modified, drug‐loaded EVs exhibit enhanced cytotoxicity compared to unmodified EVs and free drug, suggesting this system may lower the effective
Maja Dorfner   +7 more
wiley   +1 more source

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