Results 201 to 210 of about 89,656 (296)

‘A Perpetually Disintegrating Synthesis’: Sartre on Bad Faith, Good Faith, and the Projects of Selfhood

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract An oft‐overlooked aspect of Sartre’s concept of selfhood is his rejection of good faith and sincerity as normative ideals. We argue that Sartre’s paradoxical treatment of good faith – claiming both that it is a manifestation of bad faith and the antithesis of it – holds a key to understanding Sartre’s account of selfhood.
Mark A. Wrathall, Wanda von Knobelsdorff
wiley   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

F IS FOR FALCON: THE TRUE STORY OF THE ‘NOVELLE’

open access: yesGerman Life and Letters, EarlyView.
ABSTRACT This article takes a closer look at the Boccaccio story upon which Paul Heyse based his famous ‘Falken‐Theorie’ of the ‘Novelle’. The essay then links Boccaccio to a general account of storytelling as an aid to survival amid the hostility of nature and human circumstances.
Michael Minden
wiley   +1 more source

Beyond Formal Agreements: EU Agencies' Cooperation with Third Countries

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
ABSTRACT Third countries' participation in European Union (EU) agencies is attracting increasing attention as venues for differentiated European integration. Research has started to vest into the host of formal agreements regulating this cooperation. However, regulatory outreach by EU agencies may be more important than it is stated de jure, as many ...
Thibaud Deruelle   +2 more
wiley   +1 more source

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