Results 101 to 110 of about 276,720 (291)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Design and Economic Analysis of Solid Control System for Coiled Tubing Drilling
Shiyou jixieTo solve the problems of high energy consumption， large floor area and insufficient environmental protection performance of traditional coiled tubing drilling （CTD） solid control system， a two-stage optimized solid control system scheme based on high ...
Yang Lin +4 more
doaj
Jurnal Teknologi LaboratoriumThe centrifugal force in the centrifuge is able to change the surface properties of bacterial cells and the inner structure, including DNA, so that it can damage bacterial cells.
Budi Prasetyo +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Centrifuge Study on the Influence of Tunnel Excavation on Piles in Sand [PDF]
, 2020 © 2020 American Society of Civil Engineers. Tunneling-induced ground movements can affect the equilibrium state of an existing pile, causing uneven settlement among pile groups and damage to connected structures.
Song, Geyang, Marshall, Alec M.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Investigation of trapping process in “Centrifuge-on-a-chip”
, 2013 'Centrifuge-on-a-chip' is a versatile and multifunctional microfluidic chip which can conduct operations of selective trapping, enrichment, labeling and solution exchange.
Jun Zhang +7 more
core +1 more source