Results 331 to 340 of about 118,231 (380)

dTAPL, A Method That Expedites the Discovery of Proteins Associated With Specific Genomic Loci in Plants

Plant Biotechnology Journal, EarlyView.
Fan Zhang, Tengfei Zhu, Conggui Peng, Zhen Zhuang, Yaping Tang, Zhi Yang, Shengbao Yang, Liyu Huang, Xu Wang   +8 more
wiley   +1 more source

Cytotoxicity of Atropisomeric [1,1′‐Binaphthalene]‐2,2′‐Diamines (BINAM) and Analogs in Human Cancer Cells: Enantioselectivity, Structure–Activity Relationships, and Mechanism

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
It is reported for the first time that atropisomeric (R)‐[1,1′‐binaphthalene]‐2,2′‐diamine (R‐BINAM, 1(R)), but not (S)‐[1,1′‐binaphthalene]‐2,2′‐diamine (S‐BINAM, 1(S)), is a moderately potent spindle poison, causing antiproliferation, depolymerization of microtubules, multipolar spindles, pericentriolar material (PCM) fragmentation, mitotic ...
Malte Eichelbaum, Patrick J. Bednarski
wiley   +1 more source

Conservation of dichromatin organization along regional centromeres. [PDF]

Cell Genom
Dubocanin D, Hartley GA, Sedeño Cortés AE, Mao Y, Hedouin S, Ranchalis J, Agarwal A, Logsdon GA, Munson KM, Real T, Mallory BJ, Eichler EE, Biggins S, O'Neill RJ, Stergachis AB.   +14 more
europepmc   +1 more source

Hierarchical Prediction and Perturbation of Chromatin Organization Reveal How Loop Domains Mediate Higher‐Order Architectures

Advanced Science, Volume 12, Issue 37, October 6, 2025.
HiCGen introduces a hierarchical deep learning framework to predict genome organization across spatial scales using DNA sequences and genomic features. The model enables cross‐cell‐type predictions and in silico perturbation analysis, revealing correlations between loop domains and higher‐order structures.
Jiachen Wei, Yue Xue, Yi Qin Gao
wiley   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source

Marking dad's centromeres: maintaining CENP-A in sperm. [PDF]

Chromosome Res
Štiavnická M, Keegan RS, Dunleavy EM.
europepmc   +1 more source

Homeostasis of DNA Hemi‐Methylation in Arabidopsis through Methylation Maintenance, DNA Replication, and Nucleosome Positioning Mechanisms

Advanced Science, Volume 12, Issue 38, October 13, 2025.
In Arabidopsis, the homeostasis of full‐ and hemi‐methylation is mainly regulated by maintenance methylation. The maintenance methylation at hemi‐methylated dyads is highly efficient but the efficiency differs at euchromatic or heterochromatic regions. Nucleosomes impair the hemi‐ to full‐methylation transition. Lagged methylation maintenance after DNA
Hengye Chen, Chenhuan Xu
wiley   +1 more source

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Meiosis is a specialized form of cell division that has different regulation and mechanisms with mitosis in numerous aspects. Particularly, meiosis I is unique and occurs only in germ cells to separate homologous chromosomes. Thus, determining how this unusual chromosome segregation behavior is established is central to understanding germ cell ...
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
wiley   +1 more source

Hypogammaglobulinemia in patients affected by limited cutaneous systemic sclerosis: Case series and review of the literature. [PDF]

J Scleroderma Relat Disord
Danieli MG, Mezzanotte C, Paladini A, Benfaremo D, Murdaca G, Moroncini G.   +5 more
europepmc   +1 more source

Research Progress on 35S rDNA and 5S rDNA in Sugarcane: Challenges and Prospects. [PDF]

Int J Mol Sci
Li X, Guo Y, Guo Z, Zhang N, Lei Y, Cai E, Deng Z, Wu J.   +7 more
europepmc   +1 more source