Results 21 to 30 of about 3,430 (239)
Toxic Peptides from the Mexican Scorpion <i>Centruroides villegasi</i>: Chemical Structure and Evaluation of Recognition by Human Single-Chain Antibodies. [PDF]
Toxins (Basel)Alternative recombinant sources of antivenoms have been successfully generated. The application of such strategies requires the characterization of the venoms for the development of specific neutralizing molecules against the toxic components. Five toxic
Riaño-Umbarila L +6 more
europepmc +2 more sources
Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion <i>Centruroides bonito</i>. [PDF]
Toxins (Basel)Five peptides were isolated from the venom of the Mexican scorpion Centruroides bonito by chromatographic procedures (molecular weight sieving, ion exchange columns, and HPLC) and were denoted Cbo1 to Cbo5.
Restano-Cassulini R +6 more
europepmc +2 more sources
Allergy, Volume 78, Issue 8, Page 2089-2108, August 2023., 2023 Abstract Insect venom allergy is the most frequent cause of anaphylaxis in Europe and possibly worldwide. The majority of systemic allergic reactions after insect stings are caused by Hymenoptera, and among these, vespid genera induce most of the systemic sting reactions (SSR). Honey bees are the second leading cause of SSR.
Gunter Johannes Sturm +10 more
wiley +1 more source
Convergent evolution of toxin resistance in animals
Biological Reviews, Volume 97, Issue 5, Page 1823-1843, October 2022., 2022 ABSTRACT Convergence is the phenomenon whereby similar phenotypes evolve independently in different lineages. One example is resistance to toxins in animals. Toxins have evolved many times throughout the tree of life. They disrupt molecular and physiological pathways in target species, thereby incapacitating prey or deterring a predator.
Jory van Thiel +10 more
wiley +1 more source
Ecology and Evolution, Volume 11, Issue 22, Page 15630-15638, November 2021., 2021 Scorpio maurus was collected and evaluated for morphometric study and sexual dimorphism analyses for the first time in Iran. 53 morphological characters of 15 specimens of each sex of S. maurus were studied. Sexual dimorphism was observed in 21 morphological characters of S. maurus based on statistical analyses.
Parisa Soltan‐Alinejad +4 more
wiley +1 more source
FEBS Open Bio, Volume 11, Issue 7, Page 1867-1892, July 2021., 2021 Buthus occitanus scorpion possesses highly toxic venom. This article describes the first proteomic screening of the Moroccan B. occitanus venom. Our findings highlight the complexity and the toxin diversity of this venom. The most representative compounds are neurotoxins.
Khadija Daoudi +8 more
wiley +1 more source
Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges
Medicinal Research Reviews, Volume 41, Issue 4, Page 2423-2473, July 2021., 2021 Abstract The KV1.3 voltage‐gated potassium ion channel is involved in many physiological processes both at the plasma membrane and in the mitochondria, chiefly in the immune and nervous systems. Therapeutic targeting KV1.3 with specific peptides and small molecule inhibitors shows great potential for treating cancers and autoimmune diseases, such as ...
Špela Gubič +9 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021 The scorpions, named Mesobuthus martensii, commonly called Quanxie (全蝎) in Chinese, have been widely used as one of the animal medicines for more than 1,000 years because of the strong toxicity of their venoms. Meanwhile, scorpions are sexually dimorphic in appearance, and many exhibit traits associated with sex‐biased gene expression, including ...
Songyu Gao +11 more
wiley +1 more source
The FASEB Journal, 2019 Scorpions from the Centruroides genus have high toxicity and it is potentially dangerous to humans. In this study we compare the effect of the crude venom of a colombiam scorpion Centruroides margaritatus ( Cm ...
Cláudia Ferreira Santos +6 more
openaire +1 more source
Revista Mexicana de Biodiversidad, 2009 Se describe Centruroides hirsutipalpus sp. nov. de la región de Minatitlán, Colima. Se compara con las especies morfológica y geográficamente más cercanas, C. elegans Thorell y C.
Javier Ponce-Saavedra, Oscar F. Francke
doaj +1 more source