Results 21 to 30 of about 3,187 (253)

Convergent evolution of toxin resistance in animals

Biological Reviews, Volume 97, Issue 5, Page 1823-1843, October 2022., 2022
ABSTRACT Convergence is the phenomenon whereby similar phenotypes evolve independently in different lineages. One example is resistance to toxins in animals. Toxins have evolved many times throughout the tree of life. They disrupt molecular and physiological pathways in target species, thereby incapacitating prey or deterring a predator.
Jory van Thiel, Muzaffar A. Khan, Roel M. Wouters, Richard J. Harris, Nicholas R. Casewell, Bryan G. Fry, R. Manjunatha Kini, Stephen P. Mackessy, Freek J. Vonk, Wolfgang Wüster, Michael K. Richardson   +10 more
wiley   +1 more source

Morphometric study and sexual dimorphism analyses in an Iranian population of Scorpio maurus (Arachnida: Scorpionidae)

Ecology and Evolution, Volume 11, Issue 22, Page 15630-15638, November 2021., 2021
Scorpio maurus was collected and evaluated for morphometric study and sexual dimorphism analyses for the first time in Iran. 53 morphological characters of 15 specimens of each sex of S. maurus were studied. Sexual dimorphism was observed in 21 morphological characters of S. maurus based on statistical analyses.
Parisa Soltan‐Alinejad, Saman Parsaei, Ali Dianat, Mahmood Nikbakhtazadeh, Kourosh Azizi   +4 more
wiley   +1 more source

Gene content evolution in the arthropods [PDF]

, 2020
Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome ...
Anstead, Clare A., Ayoub, Nadia A., Batterham, Phillip, Bellair, Michelle, Benoit, Joshua B., Binford, Greta J., Bornberg-Bauer, Erich, Chao, Hsu, Chen, Yolanda H., Childers, Christopher, Chipman, Ariel D., Dinh, Huyen, Doddapaneni, Harsha Vardhan, Dohmen, Elias, Duan, Jian J., Dugan, Shannon, Esposito, Lauren A., Friedrich, Markus, Garb, Jessica, Gasser, Robin B., Gibbs, Richard A., Glastad, Karl, Goodisman, Michael A. D., Gundersen-Rindal, Dawn E., Hackett, Kevin J., Hahn, Matthew W., Han, Yi, Handler, Alfred M., Hatakeyama, Masatsugu, Hering, Lars, Hughes, Daniel S. T., Hunter, Wayne B., Ioannidis, Panagiotis, Jayaseelan, Joy C., Kalra, Divya, Khila, Abderrahman, Korhonen, Pasi K, Lee, Carol Eunmi, Lee, Sandra L., Li, Yiyuan, Lindsey, Amelia R. I., Mayer, Georg, McGregor, Alistair P., McKenna, Duane D., Misof, Bernhard, Munidasa, Mala, Munoz-Torres, Monica, Murali, Shwetha C., Muzny, Donna M., Niehuis, Oliver, Osuji-Lacy, Nkechinyere, Palli, Subba R., Panfilio, Kristen A., Pechmann, Matthias, Perry, Trent, Peters, Ralph S., Pfrender, Michael E., Poelchau, Monica, Poynton, Helen C., Prpic, Nikola-Michael, Qu, Jiaxin, Richards, Stephen, Rotenberg, Dorith, Schal, Coby, Schoville, Sean D., Scully, Erin D., Skinner, Evette, Sloan, Daniel B., Stouthamer, Richard, Strand, Michael R., Szucsich, Nikolaus U., Thomas, Gregg W. C., Waterhouse, Robert M., Werren, John H., Wijeratne, Asela, Worley, Kim C., Young, Neil D., Zattara, Eduardo E., Zdobnov, Evgeny M.   +78 more
core   +5 more sources

Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom

FEBS Open Bio, Volume 11, Issue 7, Page 1867-1892, July 2021., 2021
Buthus occitanus scorpion possesses highly toxic venom. This article describes the first proteomic screening of the Moroccan B. occitanus venom. Our findings highlight the complexity and the toxin diversity of this venom. The most representative compounds are neurotoxins.
Khadija Daoudi, Christian Malosse, Ayoub Lafnoune, Bouchra Darkaoui, Salma Chakir, Jean‐Marc Sabatier, Julia Chamot‐Rooke, Rachida Cadi, Naoual Oukkache   +8 more
wiley   +1 more source

Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

Medicinal Research Reviews, Volume 41, Issue 4, Page 2423-2473, July 2021., 2021
Abstract The KV1.3 voltage‐gated potassium ion channel is involved in many physiological processes both at the plasma membrane and in the mitochondria, chiefly in the immune and nervous systems. Therapeutic targeting KV1.3 with specific peptides and small molecule inhibitors shows great potential for treating cancers and autoimmune diseases, such as ...
Špela Gubič, Louise A. Hendrickx, Žan Toplak, Maša Sterle, Steve Peigneur, Tihomir Tomašič, Luis A. Pardo, Jan Tytgat, Anamarija Zega, Lucija P. Mašič   +9 more
wiley   +1 more source

Sex‐Biased Gene Expression of Mesobuthus martensii Collected from Gansu Province, China, Reveals Their Different Therapeutic Potentials

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
The scorpions, named Mesobuthus martensii, commonly called Quanxie (全蝎) in Chinese, have been widely used as one of the animal medicines for more than 1,000 years because of the strong toxicity of their venoms. Meanwhile, scorpions are sexually dimorphic in appearance, and many exhibit traits associated with sex‐biased gene expression, including ...
Songyu Gao, Feng Wu, Xintong Chen, Ying Yang, Yina Zhu, Liang Xiao, Jing Shang, Xiaowei Bao, Yi Luo, Haihu Chen, Qing Liu, Oluwafemi Adeleke Ojo   +11 more
wiley   +1 more source

Centruroides toxin, a selective blocker of surface Na+ channels in skeletal muscle: voltage-clamp analysis and biochemical characterization of the receptor.

Proceedings of the National Academy of Sciences of the United States of America, 1982
Enrique Jaimovich, M Ildefonse, Jacques Barhanin, O Rougier, Michel Lazdunski   +4 more
exaly   +3 more sources

Cardiovascular effects of the scorpions Centruroides margaritatus, Centruroides limpidus and Centruroides noxius crude venom

The FASEB Journal, 2019
Scorpions from the Centruroides genus have high toxicity and it is potentially dangerous to humans. In this study we compare the effect of the crude venom of a colombiam scorpion Centruroides margaritatus ( Cm ...
Cláudia Ferreira Santos, Jessica Dayana Galíndez Céron, Alexandre Havt Bindá, Lourival D Possani, José Béltran Vidal, Manassés Claudino Fonteles, Nilberto Robson Falcão Nascimento   +6 more
openaire   +1 more source

Evidencias morfológicas y moleculares que validan como especie a Centruroides tecomanus (Scorpiones, Buthidae)

Revista Mexicana de Biodiversidad, 2009
SE PRESENTAN EVIDENCIAS MORFOLÓGICAS Y MOLECULARES PARA RECONOCER A CENTRUROIDES LIMPIDUS TECOMANUS HOFFMANN (SCORPIONES: BUTHIDAE) COMO ESPECIE VÁLIDA Y NO COMO UNA SUBESPECIE DE CENTRUROIDES LIMPIDUS (KARSCH). SE DIAGNOSTICA LA ESPECIE.
ÓSCAR F. FRANCKE B., JAVIER PONCE SAAVEDRA, ERASTO HERNÁNDEZ CALDERÓN, HORACIO CANO CAMACHO   +3 more
doaj   +1 more source

Species delimitation and morphological divergence in the scorpion Centruroides vittatus (Say, 1821): insights from phylogeography. [PDF]

PLoS ONE, 2013
Scorpion systematics and taxonomy have recently shown a need for revision, partially due to insights from molecular techniques. Scorpion taxonomy has been difficult with morphological characters as disagreement exists among researchers with character ...
Tsunemi Yamashita, Douglas D Rhoads
doaj   +1 more source