Results 91 to 100 of about 104,518 (269)

Crystal structure and biophysical characterisation of the enterococcal foldase PpiC, a cross‐opsonic antigen against gram‐positive nosocomial pathogens

open access: yesThe FEBS Journal, EarlyView.
PpiC is an enterococcal lipoprotein endowed with both Peptidyl‐prolyl cis‐trans isomerase (PPIase) and foldase activities. It is a potential target for novel antimicrobials and a promising vaccine antigen. We determined the crystal structure of the enzyme, showing that PpiC adopts a dimeric organisation embedding two catalytic parvulin‐type PPIase ...
Valeria Napolitano   +7 more
wiley   +1 more source

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov   +2 more
wiley   +1 more source

Dynamics between antibiotic drug use and resistance : An economic approach [PDF]

open access: yes
In Europe, the emergence and spread of antibiotic resistance (AMR) has become a serious public health threat. Rational antibiotic policy, combined with enforcement of infection control practices are key strategies to combat AMR in the hospital setting ...
Frank, Uwe, Kaier, Klaus
core  

Pharmacokinetics of Ampicillin Trihydrate in Plasma, Interstitial, and Peritoneal Fluid Following Intraperitoneal or Intramuscular Administration in Steers at the Beginning of a Standing Flank Laparotomy

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Prophylactic and perioperative use of antibiotics is common prior to abdominal surgery in cattle for minimizing the risk of postoperative infections. Yet, there is little information on drug concentrations at sites of potential infections following surgical procedures. The objective of this study was to compare the concentrations in the plasma,
Danielle A. Mzyk   +4 more
wiley   +1 more source

The role of antibiotics in preventing surgical complications in periodontology and implant dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription.
Zhaozhao Chen   +3 more
wiley   +1 more source

The diagnosis and treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease and chronic bronchitis. [PDF]

open access: yes, 2010
The syndrome of chronic obstructive pulmonary disease (COPD) consists of chronic bronchitis (CB), bronchiectasis, emphysema, and reversible airway disease that combine uniquely in an individual patient.
Albertson, Timothy E   +2 more
core  

Effect of Antibiotics With Anaerobic Coverage on Graft‐Versus‐Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta‐Analysis

open access: yesTransplant Infectious Disease, EarlyView.
ABSTRACT Background Broad‐spectrum antibiotics are standard for febrile neutropenia (FN) in allogeneic hematopoietic stem cell transplantation (HSCT) but may disrupt gut microbiota, increasing the risk of graft‐versus‐host disease (GVHD). However, current evidence on the effects of anaerobic versus limited anaerobic antibiotic coverage on GVHD‐related
Hiroshi Ito   +5 more
wiley   +1 more source

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