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Randomized clinical trial of intrauterine cephapirin infusion in dairy cows for the treatment of purulent vaginal discharge and cytological endometritis [PDF]

open access: yesJournal of Dairy Science, 2015
The objectives of this study were to quantify the effect of an intrauterine infusion of cephapirin on reproductive performance at first service of postpartum dairy cows affected by purulent vaginal discharge (PVD) and cytological endometritis (ENDO ...
José DENIS-ROBICHAUD, Jocelyn Dubuc
exaly   +2 more sources
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Cephapirin-Induced Neutropenia

Chemotherapy, 2009
Five cases (3.5%) of reversible cephapirin-induced neutropenia were observed in 132 patients receiving this antibiotic. The disorder was severe (agranulocytosis) in 3 cases. Simultaneous maculopapular rash was observed in all of them and in 4 cases fever occured. All the cases observed were female (p not significant).
C, Vidal Pan   +5 more
openaire   +2 more sources

The role of the kidney in the elimination of cephapirin in man

Journal of Pharmacokinetics and Biopharmaceutics, 1975
A pharmacokinetic model was developed to describe the absorption, distribution, metabolism, and excretion of cephapirin and its major metabolite, desacetylcephapirin, following intravenous and intramuscular administration of cephapirin in healthy adult subjects.
B E, Cabana   +6 more
openaire   +2 more sources

Effect of milk fraction on concentrations of cephapirin and desacetylcephapirin in bovine milk after intramammary infusion of cephapirin sodium

Journal of Veterinary Pharmacology and Therapeutics, 2008
Clinical mastitis in dairy cows is commonly treated with intramammary (IMM) antimicrobial agents. Pharmacokinetic data are used to design treatment regimens and determine withholding times. In some pharmacokinetic studies, investigators measure antimicrobial concentrations in foremilk, whereas in others, they use bucket milk or do not specify the milk ...
R M, Stockler   +4 more
openaire   +2 more sources

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