Results 161 to 170 of about 159,979 (309)

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate-to-Severe Atopic Dermatitis: A Phase IV, Non-Randomized, Open-Label, Parallel-Group Clinical Study. [PDF]

MedComm (2020)
Liu T, Chen S, Zhao W, Di D, Liu J, Tian Y, Luo Y, Xu Y, Xue R, Ye L, Pei X, Yu B, Wang Y, Zhang J, Yu X, Wen W, Yuan L, Ji S, Hu C, Shen D, Guo Y, Liang Y.   +21 more
europepmc   +1 more source

Helicopter from Cer Aviation, Tampa

, 1980
Pilot from Cer Aviation landing a helicopter in Tampa, Florida.https://digitalcommons.usf.edu/gandy/3394/thumbnail ...
Gandy, George Skip, IV
core  

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

A fuzzy-augmented deep learning pipeline for multilingual natural language processing from handwritten script: a Tamil case study. [PDF]

Front Artif Intell
Kumar A H, Aarthi B, Kumaran K, Saranya G, Venkatram C P.   +4 more
europepmc   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Hypertensive stretch regulates endothelial cell inflammation and apoptosis through ceramide metabolism. [PDF]

Am J Physiol Cell Physiol
Pietromicca-Victor JG, Chitkara S, Muñoz E, Manzar ZA, Bharathi Rajan AP, Bieberich E, Atilla-Gokcumen GE, Alevriadou BR.   +7 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Exploring Wav2Vec2 XLSR-53 and Whisper-small for Telugu language speech-to-text: a fine-tuning approach. [PDF]

Front Artif Intell
Dar MA, Kammula SGK, Pushparaj J, Santhosh VS.   +3 more
europepmc   +1 more source

CER in 2010 [PDF]

Cancer, 2010
openaire   +1 more source