Results 141 to 150 of about 44,836 (309)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

AISLAMIENTO DE MATERIA INSAPONIFICABLE A PARTIR DE CACHAZA UTILIZANDO ETANOL COMO SOLVENTE

open access: yesRevista Centro Azúcar, 2016
En este artículo se propone una metodología para la obtención de materia  insaponificable a partir de la cachaza de caña de azúcar, en la que solamente se emplea  etanol 96 °GL como solvente. La cera se extrae de la cachaza con etanol (con una  pureza de
Inés María San Anastacio Rebollar   +2 more
doaj  

Advancing the Science of Surgical Education: Reflections From the 2025 University of Melbourne Department of Surgery Research Showcase

open access: yesANZ Journal of Surgery, EarlyView.
Key themes from the 2025 University of Melbourne Department of Surgery Research Showcase. Advances in simulation‐based training, robotic and technology‐enhanced learning, Artificial Intelligence–enabled assessment, and workforce equity were highlighted as drivers of surgical education innovation.
Yuchen Luo   +17 more
wiley   +1 more source

CERA as a Sustainable Driver of Family Medicine Research. [PDF]

open access: yesAnn Fam Med
Ho TF   +3 more
europepmc   +1 more source

Refining effect size measures and classification for differential item functioning: Toward unified guidelines across methods

open access: yesBritish Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Differential Item Functioning (DIF) analysis is used to identify potentially biased items in multi‐item measurements. In addition to testing the statistical significance, it is essential to evaluate the practical significance of DIF through effect size measures.
Michaela Cichrová   +2 more
wiley   +1 more source

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

open access: yesBrain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova   +11 more
wiley   +1 more source

An Integrated Cardiac Microtissue Proteome Map Extends Therapeutic Remodeling by Nanovesicles. [PDF]

open access: yesMol Cell Proteomics
Lozano J   +10 more
europepmc   +1 more source

Receptor kinetics: Binding flux‐based approaches offer complementary insight into how ligand binding evolves with time

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Binding kinetics are essentially based on rate constants. Yet, this view has been challenged by the idea that ‘binding fluxes’ are dynamic and therefore more relevant. Those fluxes refer to the rate at which a target/receptor changes from one state into another through ligand/drug binding or a conformational change.
Georges Vauquelin   +2 more
wiley   +1 more source

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