Results 11 to 20 of about 39,798 (299)

A Philosophical Journey into the Anthropocene: Discovering Terra Incognita

open access: yes, 2023
A Philosophical Journey into the Anthropocene: Discovering Terra Incognita presents the Anthropocene not only as a geological epoch, but rather as the potential métarécit of our age and the most faithful expression of the current zeitgeist.
Agostino Cera
core   +1 more source

Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery

open access: yesAngewandte Chemie, EarlyView.
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne   +5 more
wiley   +2 more sources

3D SURVEY TECHNOLOGIES TO DOCUMENT AND SUPPORT MICAELIC RUPESTRIAN ARCHITECTURE PRESERVATION. A CASE STUDY [PDF]

open access: yes, 2023
The paper presents the actions conducted for the case study of the Hermitage of San Michele a le Grottelle, in Padula (Italy) in the framework of the scientific collaboration between the Urban\Eco Interdepartmental Research Centre and the Diocese of ...
V. Cera, Valeria Cera
core   +1 more source

Impact of the Reduction of Diesel Fuel Subsidy in the Design of an Off-Grid Hybrid Power System: A Case Study of the Bellavista Community in Ecuador

open access: yesEnergies, 2021
This paper presents a technical, economic, and environmental analysis and optimization of the impact of the reduction of diesel fuel subsidy in the design of an off-grid hybrid power system (OHPS).
Ruben Hidalgo-Leon   +6 more
doaj   +1 more source

Totipotency segregates between the sister blastomeres of two-cell stage mouse embryos

open access: yesScientific Reports, 2017
Following fertilization in mammals, it is generally accepted that totipotent cells are exclusive to the zygote and to each of the two blastomeres originating from the first mitotic division. This model of totipotency was inferred from a minority of cases
E. Casser   +6 more
doaj   +1 more source

CARACTERÍSTICAS DA SUARDA E COLORAÇÃO DA LÃ LAVADA EM DIFERENTES REGIÕES DO VELO EM FUNÇÃO DO MEIO AMBIENTE

open access: yesCiência Rural, 1994
RESUMO Amostras de lã de quatro regiões do velo (lombo, paleta, quarto e costilhar) de 20 borregas Ideal foram analisadas quanto às percentagens de cera e suor, características do suor (pH, cor e absorbância) e coloração e brilho da lã.
Magda Vieira Benavides   +2 more
doaj   +1 more source

FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility

open access: yesFrontiers in Endocrinology, 2021
Introduction and ObjectivesAbout 30-75% of infertile men are diagnosed with idiopathic infertility, thereby lacking major causative factors to explain their impaired fertility status.
Henrike Krenz   +4 more
doaj   +1 more source

Dose-dependent effect of continuous erythropoietin receptor activator on cardiac autonomic nervous activity and cardiovascular events in patients treated with online hemodiafiltration

open access: yesZaporožskij Medicinskij Žurnal, 2019
The purpose of the work was to determine the effect of continuous erythropoietin receptor activator (CERA) on the autonomic regulation of cardiac activity and cardiovascular events in patients treated with online hemodiafiltration (HDF). Materials and
N. M. Stepanova   +5 more
doaj   +1 more source

A qualitative exploration of how a community engagement approach influences community and health worker perceptions related to family planning service delivery in Togo

open access: yesFrontiers in Reproductive Health
BackgroundThere is a growing body of evidence that asserts community engagement approaches can improve the quality of reproductive health services. Family planning (FP) programs in Togo are implementing such approaches, which aim to mobilize both health ...
Leanne Dougherty   +12 more
doaj   +1 more source

Assessing the Impact of Climate Variability on Olive Yield in Turkiye

open access: yesGlobal Environment
Despite the central role of olive production in the Mediterranean economy, economic studies assessing the impact of climate variability on olive yield remain limited in scope and number.
Sevil Acar, Oguz Tutal
doaj   +1 more source

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