Results 61 to 70 of about 46,118 (147)
ABSTRACT Background Upadacitinib (UPA) is the first oral Janus kinase (JAK) inhibitor approved for the treatment of Crohn's disease (CD). Real‐world data, particularly from large nationwide cohorts, remain limited. This study aimed to evaluate the real‐world effectiveness, safety, and treatment persistence of UPA in patients with CD.
M. Iborra +51 more
wiley +1 more source
The Challenge of Adherence in Wilson Disease: An Opportunity for Nurse‐Led Interventions
ABSTRACT Background and Aims Life‐long treatment is critical in Wilson disease (WD), a rare genetic disease leading to copper accumulation with hepatic and extrahepatic manifestations. Poor adherence is a well‐known contributor to unfavourable clinical outcomes.
Anna Miralpeix +8 more
wiley +1 more source
Conexões Ecológicas no Paleoterritório do Café
A produção de café no Brasil durante o século XIX foi uma das maiores alavancas para a economia da época. As terras do Vale do Rio Paraíba do Sul foram pródigas produtoras por um intenso, mas breve período de tempo.
Adi Estela Lazos Ruíz +4 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Changes in land use have generated a new landscape configuration in the Andino orobiome (mountain range) of the tropical Andes, resulting in a mosaic of cultivation and pastures interrupted by small fragments of forest and live fences.
Javier Otero, Miren Onaindia
doaj
Se analizó la composición de especies y se evaluó la eficiencia en la remoción de estiércol vacuno por escarabajos del estiércol de la subfamilia Scarabaeinae durante las temporadas de lluvias y secas en 2 zonas ganaderas del norte de Veracruz con ...
Karen Pamela Miranda-Flores +4 more
doaj +1 more source
A dinâmica de uso da terra no Sudeste do Pará caracterizou-se pela conversão das áreas de floresta em roçados e pastagens. No caso das pastagens, a mudança de uso do solo, associada ao seu manejo inadequado, refletiu-se na degradação das pastagens, baixa produtividade animal e escassez de madeira.
Heloiza Sousa de Andrade Nunes +4 more
openaire +3 more sources
ABSTRACT Prisons offer a critical opportunity for hepatitis C virus (HCV) elimination, yet current data from Danish correctional facilities are sparse. We conducted a cross‐sectional study in 16 prisons across Eastern Denmark between October 2022 and August 2024, enrolling 651 incarcerated individuals.
Jonas Demant +10 more
wiley +1 more source
Sistemas silvipastoris com palanques vivos: estudo comparativo sobre a adoção de SSP entre os produtores de leite da capital catarinense da agroecologia. [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Curso de Agronomia.A busca por uma produção pecuária mais sustentável é de extrema importância para o estado de Santa Catarina, uma vez que esta atividade está ...
Pitton Filho, Darci
core
Abstract Drawing is a classical teaching strategy in anatomy. While teachers' drawings can foster learning, teaching anatomy using video lectures can be challenging. According to the cognitive theory of multimedia learning (CTML), the learning effect of a video lecture could be related to the presence of the drawing hand of the teacher.
Martin M. Bertrand +3 more
wiley +1 more source

