Results 41 to 50 of about 654,125 (225)

A novel inhibitory nucleo-cortical circuit controls cerebellar Golgi cell activity

open access: yeseLife, 2015
The cerebellum, a crucial center for motor coordination, is composed of a cortex and several nuclei. The main mode of interaction between these two parts is considered to be formed by the inhibitory control of the nuclei by cortical Purkinje neurons.
Lea Ankri   +7 more
doaj   +1 more source

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

open access: yes, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H   +4 more
core   +2 more sources

Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum

open access: yesNeural Development, 2011
Background The cerebellum is composed of a diverse array of neuronal subtypes. Here we have used a candidate approach to identify Zac1, a tumor suppressor gene encoding a zinc finger transcription factor, as a new player in the transcriptional network ...
Schuurmans Carol   +6 more
doaj   +1 more source

Control of voluntary and optogenetically perturbed locomotion by spike rate and timing of neurons of the mouse cerebellar nuclei

open access: yeseLife, 2018
Neurons of the cerebellar nuclei (CbN), which generate cerebellar output, are inhibited by Purkinje cells. With extracellular recordings during voluntary locomotion in head-fixed mice, we tested how the rate and coherence of inhibition influence CbN cell
R. Sarnaik, I. Raman
semanticscholar   +1 more source

The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]

open access: yes, 2016
The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A   +4 more
core   +2 more sources

The deep cerebellar nuclei to striatum disynaptic connection contributes to skilled forelimb movement

open access: yesCell Reports, 2023
Summary: Cerebellar-thalamo-striatal synaptic communication has been implicated in a wide range of behaviors, including goal-directed actions, and is altered in cerebellar dystonia.
Rubén Contreras-López   +4 more
doaj   +1 more source

Moderate Renal Failure Accentuates T1 Signal Enhancement in the Deep Cerebellar Nuclei of Gadodiamide-Treated Rats

open access: yesInvestigative Radiology, 2016
Objectives The purpose of this preclinical study was to investigate whether moderate chronic kidney disease is a factor in potentiating gadolinium (Gd) uptake in the brain.
Marlène Rasschaert   +7 more
semanticscholar   +1 more source

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit

open access: yesNature Communications, 2023
Synaptic adhesion molecules (SAMs) shape the structural and functional properties of synapses and thereby control the information processing power of neural circuits.
Alessandra Sclip, Thomas C. Südhof
doaj   +1 more source

The spino-bulbar-cerebellar pathway: organization and neurochemical properties of spinal cells that project to the lateral reticular nucleus in the rat [PDF]

open access: yes, 2015
In addition to classical spinocerebellar pathways, the cerebellum receives information from the spinal cord indirectly via spino-bulbar-cerebellar systems. One of the structures in this pathway is the lateral reticular nucleus (LRt).
Huma, Zilli, Maxwell, David J.
core   +2 more sources

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