Results 121 to 130 of about 12,993,017 (350)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Visual stimulation and cerebral activation

Contemporary Engineering Sciences, 2014
Korean society has seen a surge in the inflow of information, accompanied by colors and lights, with the emergence and technological advancement of devices such as TVs and smart phones. Human beings receive a significant proportion of their information visually. Among the five senses (visual, auditory, olfactory, gustatory, and tactile).
Son, Byung Rak, Kim, Joo Gon, Shin, Jeong-Hoon   +2 more
openaire   +2 more sources

Cerebral venous congestion alters CNS homeostatic plasticity, evoking tinnitus-like behavior

Cell & Bioscience
Background Brain function and neuronal activity depend on a constant supply of blood from the cerebral circulation. The cerebral venous system (CVS) contains approximately 70% of the total cerebral blood volume; similar to the cerebral arterial system ...
Huimin Wei, Huimin Jiang, Yifan Zhou, Lu Liu, Wei Ma, Shanshan Ni, Chen Zhou, Xunming Ji   +7 more
doaj   +1 more source

The Effect of Movement Rate and Complexity on Functional Magnetic Resonance Signal Change During Pedaling [PDF]

, 2012
We used functional magnetic resonance imaging (fMRI) to record human brain activity during slow (30 RPM), fast (60 RPM), passive (30 RPM), and variable rate pedaling. Ten healthy adults participated.
Mehta, Jay P., Schindler-Ivens, Sheila M., Schmit, Brian D., Verber, Matthew D., Wieser, Jon A.   +4 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Protective effects of Echium amoenum Fisch. and C.A. Mey. against cerebral ischemia in the rats

Advanced Biomedical Research, 2015
Background: This study was designed to evaluate the protective effect of Echium amoenum total anthocyanin extract (ETAE) on partial/transient cerebral ischemia in the rats.
Leila Safaeian, Abolfazl Azami Tameh, Alireza Ghannadi, Elmira Akbari Naghani, Hamed Tavazoei, Samaneh Sadat Alavi   +5 more
doaj   +1 more source

The effects of blurred visual inputs with different levels on the cerebral activity during free level walking. [PDF]

Front Neurosci, 2023
Ao M, Ren S, Yu Y, Huang H, Miao X, Ao Y, Wang W.   +6 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Lysine and arginine reduce the effects of cerebral ischemic insults and inhibit glutamate-induced neuronal activity in rats

Frontiers in Integrative Neuroscience, 2010
Intravenous administration of arginine was shown to be protective against cerebral ischemic insults via nitric oxide production and possibly via additional mechanisms.
Takashi Kondoh, Takashi Kondoh, Makiko Kameishi, Hruda N Mallick, Taketoshi Ono, Kunio Torii   +5 more
doaj   +1 more source

Effect of Indoor Forest Bathing on Reducing Feelings of Fatigue Using Cerebral Activity as an Indicator. [PDF]

Int J Environ Res Public Health, 2022
Imamura C, Sakakibara K, Arai K, Ohira H, Yamaguchi Y, Yamada H.   +5 more
europepmc   +1 more source