Results 1 to 10 of about 23,332 (215)

Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]

, 2016
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
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Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, Volume 36, Issue 34, 27 April 2026.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Cerebral Arterial Air Embolism Associated with Mechanical Ventilation and Deep Tracheal Aspiration

Case Reports in Pulmonology, 2012
Arterial air embolism associated with pulmonary barotrauma has been considered a rare but a well-known complication of mechanical ventilation. A 65-year-old man, who had subarachnoid hemorrhage with Glasgow coma scale of 8, was admitted to intensive care
S. Gursoy, C. Duger, K. Kaygusuz, I. Ozdemir Kol, B. Gurelik, C. Mimaroglu   +5 more
doaj   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Targeted Thrombolysis via CCR2‐Engineered Macrophage‐Mimicking Microbubbles Safely Ablates Venous, Arterial, and Microvascular Thrombosis

Advanced Science, Volume 13, Issue 23, 23 April 2026.
CCR2‐Enhanced Macrophage Membrane–Camouflaged Microbubbles for MCP‐1–Mediated Thrombus Targeting and Ultrasound‐Triggered Urokinase Release. ABSTRACT The clinical management of thrombosis, a primary cause of death worldwide, is hampered by the limitations of current thrombolytic agents, including short half‐life and high risk of off‐target bleeding ...
Buying Li, Changjin Lu, Shijie Gao, Dandan Chen, Xue Heng, Kibret Mequanint, Malcolm Xing, Gaoxing Luo, Haisheng Li   +8 more
wiley   +1 more source

Acute Invasive Pulmonary Aspergillosis With CNS Dissemination in an Immunocompetent Individual: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Invasive pulmonary aspergillosis can occur in patients without classical immunosuppression, particularly those with COPD and corticosteroid exposure. Early recognition, prompt antifungal therapy, and vigilance for neurological symptoms are essential to prevent central nervous system dissemination, which carries high mortality and significant ...
Barbare Khatiashvili, Sarah Saife, Islam Rajab, Malina Mohtadi, Arham Hazari, Ghassan Makhoul, Aqsa Zoey Sorathia, Ahmad Huzien, Shivanck Upadhyay   +8 more
wiley   +1 more source

Cerebral air embolism as a complication of peptic ulcer in the gastric tube: case report

BMC Gastroenterology, 2011
Background The reported incidence of ulcer formation in the gastric tube in esophageal replacement is rare. Case Presentation This is the first report of a case of cerebral air embolism as a result of spontaneous perforation of an ulcer in the ...
Suzuki Takahisa, Ando Takafumi, Usami Akihisa, Shinoda Masataka, Takashi Hitomi, Murayama Mutsumi, Uchiyama Isako, Morise Kazuhiro, Endo Shinya, Haruki Nobuhiro, Tashiro Kazuhiro, Goto Hidemi   +11 more
doaj   +1 more source

Paradoxical Gas Embolism During Laparoscopic Cholecystectomy With Postoperative Acute Cerebral Infarction: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Gas embolism is a serious complication in laparoscopic cholecystectomy. Intraoperative real‐time transesophageal echocardiography is helpful for diagnosis. We present a case of a 61‐year‐old man who underwent laparoscopic cholecystectomy and experienced circulatory shock.
Zhengxiao Lai, Yuling Tang, Xuejie Li
wiley   +1 more source

Hyperviscosity‐Related Ischemic Stroke in an Adolescent With Unrepaired Tetralogy of Fallot: A Case Report From a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Chronic hypoxemia in uncorrected TOF causes compensatory erythrocytosis and hyperviscosity, predisposing to cerebrovascular complications. Stroke in this context is rare but clinically significant, especially in resource‐limited settings where access to imaging and
Ayenew A. Wolie, Chernet T. Mengistie, Biruk T. Mengistie, Elleni D. Mulatu, Rahel N. Teferi, Birhanu T. Andeta, Gedefaw T. Minwagaw   +6 more
wiley   +1 more source

Bypass grafting operations using conventional technique with off-pump coronary artery bypass grafting in two identical groups conducted at the Penang Hospital (1999-2000) [PDF]

, 2001
This is a prospective study conducted at the Department of Cardiothoracic Surgery, Penang Hospital, Penang, with a total of one hundred patients were studied over a period of one year between January 1999 to January 2000. Fifty patients who had undergone
Kasinathan, Vasantha
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