Results 91 to 100 of about 74,041 (175)

Modeling Perforator Occlusion After Flow Diversion

open access: yesInternational Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 8, August 2026.
Fibrin accumulation occurred in all jailed branches, matching the results of the animal experiments. Similarly, we show the trend of jailed branches having more fibrin accumulation the more distal they are, matching the greater area of occlusion seen in vivo for successively distal fully jailed branches.
Laurel Marsh   +8 more
wiley   +1 more source

Exercise and Circadian Rhythm Regulation: Mechanisms, Resilience, and Therapeutic Potential for Neurological Diseases

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Exercise acts as a non‐photic zeitgeber that enhances circadian rhythm alignment, reduces neuroinflammation and oxidative stress, and supports neuroprotection in CNS diseases, including stroke and Alzheimer's disease. ABSTRACT Background Circadian rhythms regulate sleep–wake cycles, hormonal secretion, metabolism, and immune responses.
Munehiro Demura   +4 more
wiley   +1 more source

Development and Validation of an Interpretable Machine Learning‐Based Clinical Prediction Model for Short‐Term Mortality in Intracerebral Hemorrhage With Thrombocytopenia: A Multicenter Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In this study, we developed and validated a clinical prediction model for the early prediction of short‐term mortality in patients with intracerebral hemorrhage complicated by thrombocytopenia. The model demonstrated good internal discrimination and acceptable external performance and may serve as a complementary tool for individualized risk ...
Dachang Qiu   +5 more
wiley   +1 more source

Ruptured aneurysm of the middle cerebral artery with cerebral herniation treated with Woven EndoBridge via distal radial artery access: a case report

open access: yesJournal of Medical Case Reports
Background Ruptured intracranial aneurysm (RIA) is the leading cause of spontaneous subarachnoid hemorrhage (SAH), with a high disability and mortality rate.
Yi Qing   +3 more
doaj   +1 more source

Topographical Patterns of Intraventricular Hemorrhage as a Novel Prognostic Imaging Biomarker in Intracerebral Hemorrhage

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study developed and externally validated the IVH topographical score (ITS) based on 11 IVH topographical patterns and clinical variables. The ITS classifies IVH patterns into four risk levels (0–3 points) and integrates GCS (3–8: 1 point), ICH volume (≥ 20 mL: 1 point), and hydrocephalus (4 points).
Ao Chen   +5 more
wiley   +1 more source

Vorinostat Mitigates Early Brain Injury Following Subarachnoid Hemorrhage Through Modulation of the C3aR1/TGF‐β/Smad Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
C3aR1 mediates microglial activation after SAH in part through the TGF‐β/Smad signaling pathway. Vorinostat alleviates early brain injury after SAH by reducing C3aR1 levels. ABSTRACT Background Excessive microglial activation after subarachnoid hemorrhage (SAH) contributes to early brain injury (EBI) and poor clinical outcomes.
Chonghui Zhang   +5 more
wiley   +1 more source

Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Cardiovascular disease arises from lifelong accumulation of traditional and emerging risk factors that converge on shared pathophysiological pathways, leading to diverse clinical outcomes, and can be mitigated through integrated screening, prevention, and precision therapies. ABSTRACT Cardiovascular diseases (CVDs) remain the leading cause of morbidity
Mowei Kong   +6 more
wiley   +1 more source

Toward Autonomous Clinics: Human–Robot Collaboration in Clinical Care

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This graphical abstract summarizes the conceptual structure of human–robot collaboration (HRC) for autonomous clinical systems. The framework is organized around a dual‐brain architecture in which a professional brain supports clinical reasoning tasks such as diagnosis, image analysis, treatment planning, and patient monitoring, while a physical brain ...
Xinyuan Wu   +8 more
wiley   +1 more source

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE‐A Cohort of 1.2 Million Surgeries

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen   +15 more
wiley   +1 more source

Intracerebral Haemorrhage in the Top End of the Northern Territory; Risk Factors, Outcomes and the Presence of Cerebral Amyloid Angiopathy in Indigenous Peoples

open access: yesAustralian Journal of Rural Health, Volume 34, Issue 4, August 2026.
ABSTRACT Objective The prevalence of intracranial haemorrhage (ICH) and cerebral amyloid angiopathy (CAA) in the Northern Territory (NT) is unknown. This study aims to improve knowledge of haemorrhagic stroke in the NT, to evaluate the relevance of CAA and examine its association with chronic kidney disease (CKD).
Marianna Diamandopoulos   +2 more
wiley   +1 more source

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