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Brain function depends on close matching between metabolic demands for oxygen and nutrients and removal of cellular waste. This requires continuous regulation of cerebral blood flow (CBF) to match the high metabolic demands. The topic of this chapter is cerebral pressure regulation i.e., the intrinsic response of the cerebral vasculature to changes in ...
Parisa Nikrouz +2 more
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Parisa Nikrouz +2 more
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Cerebral Autoregulation and Syncope
Progress in Cardiovascular Diseases, 2007Whatever the pathogenesis of syncope is, the ultimate common cause leading to loss of consciousness is insufficient cerebral perfusion with a critical reduction of blood flow to the reticular activating system. Brain circulation has an autoregulation system that keeps cerebral blood flow constant over a wide range of systemic blood pressures. Normally,
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Assessment of cerebral pressure autoregulation
Current Opinion in Anaesthesiology, 2002Cerebral pressure autoregulation, a sensitive homeostatic mechanism important for the control of cerebral blood flow, is impaired by disease pathology and some drugs commonly used during anaesthesia. Therefore, the assessment of cerebral pressure autoregulation can help optimize cerebral blood flow in patients who have suffered neurological insults. In
RASULO, Francesco Antonio +2 more
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Cerebral Autoregulation in Orthostatic Intolerance
Annals of the New York Academy of Sciences, 2001Abstract: Many of the primary symptoms of orthostatic intolerance (fatigue, diminished concentration) as well as some of the premonitory symptoms of neurally mediated syncope (NMS) are thought to be due to cerebral hypoperfusion. Transcranial Doppler measurements of middle cerebral artery blood velocity (CBV) is at present the only technique for ...
R, Schondorf, J, Benoit, R, Stein
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The frequency response of cerebral autoregulation
Journal of Applied Physiology, 2013The frequency-response of pressure autoregulation is not well delineated; therefore, the optimal frequency of arterial blood pressure (ABP) modulation for measuring autoregulation is unknown. We hypothesized that cerebrovascular autoregulation is band-limited and delineated by a cutoff frequency for which ABP variations induce cerebrovascular ...
Charles D, Fraser +9 more
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Phase dynamics in cerebral autoregulation
American Journal of Physiology-Heart and Circulatory Physiology, 2005Complex continuous wavelet transforms are used to study the dynamics of instantaneous phase difference Δφ between the fluctuations of arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) in a middle cerebral artery. For healthy individuals, this phase difference changes slowly over time and has an almost uniform distribution for the ...
Miroslaw, Latka +5 more
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Clinical Significance of Cerebral Autoregulation
2002Disturbed cerebral autoregulation is believed to be associated with an unfavourable outcome following head injury. Previously, using ICP monitoring and transcranial Doppler ultrasonography, we investigated whether cerebral response to spontaneous variations in arterial pressure (ABP) or cerebral perfusion pressure (CPP) provide reliable information on ...
M, Czosnyka +3 more
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Influence of nitroprusside on cerebral pressure autoregulation
Neurosurgery, 1979The authors studied 10 cats to assess the question of abolition of cerebral autoregulation attendant on the use of nitroprusside for hypotensive anesthesia. After the establishment of stable base line parameters, a continuous infusion of sodium nitroprusside was begun in a dose sufficient to maintain a mean systemic arterial pressure of 65 mm Hg ...
M H, Weiss +5 more
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Cerebrovascular and brain metabolism reviews, 1990
Autoregulation of blood flow denotes the intrinsic ability of an organ or a vascular bed to maintain a constant perfusion in the face of blood pressure changes. Alternatively, autoregulation can be defined in terms of vascular resistance changes or simply arteriolar caliber changes as blood pressure or perfusion pressure varies.
Paulson, O B +2 more
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Autoregulation of blood flow denotes the intrinsic ability of an organ or a vascular bed to maintain a constant perfusion in the face of blood pressure changes. Alternatively, autoregulation can be defined in terms of vascular resistance changes or simply arteriolar caliber changes as blood pressure or perfusion pressure varies.
Paulson, O B +2 more
openaire +1 more source