Results 271 to 280 of about 580,671 (347)

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source

Cerebral Blood Flow Responses to Trigeminal Olfactory Stimulation and Their Nicotinic Cholinergic Regulation in Anesthetized Rats. [PDF]

Eur J Neurosci
Morihara D, Moriya J, Kagitani F, Uchida S.   +3 more
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Mapping cerebral blood flow in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and orthostatic intolerance: insights from a systematic review. [PDF]

J Transl Med
Christopoulos EM, Tantanis D, Huang K, Schneider-Futschik EK, Gooley PR, Moneghetti KJ, Armstrong CW.   +6 more
europepmc   +1 more source

Detecting Awareness in the Intensive Care Unit Using Functional Near‐Infrared Spectroscopy

Annals of Neurology, EarlyView.
Objective Signs of awareness after acute severe brain injury are critical for informing goals‐of‐care decisions, ranging from the continuation of aggressive life‐sustaining therapy to comfort‐focused end‐of‐life measures. However, awareness may go undetected in some critically ill patients when assessed using bedside behavioral neurological examination.
Karnig Kazazian, Jack de Jeu, Androu Abdalmalak, Sergio L. Novi, Matthew Kolisnyk, Garima Gupta, Laura E. Gonzalez‐Lara, Teneille E. Gofton, Loretta Norton, Derek B. Debicki, Adrian M. Owen   +10 more
wiley   +1 more source

Biomedical Applications of Nanozymes: An Enzymology Perspective

Angewandte Chemie, EarlyView.
With a lens of enzymology, this review compares nanozymes with enzymes using the Michaelis‐Menten model and differences in KM and kcat along with catalysis in complex biological environment. The implications of these differences in biomedical applications of nanozymes are then described with a statistical analysis of the trend of therapeutic use of ...
Vasily G. Panferov, Xiaohan Zhang, Ka‐Ying Wong, Jung Heon Lee, Juewen Liu   +4 more
wiley   +2 more sources

Clinical and Laboratory Correlates of Cerebral Blood Flow Velocities and Risks for Stroke Among Steady-State Sickle Cell Anemia Children: A Cross-Sectional Study. [PDF]

Cureus
Oderanti OC, Oninla SO, Akintola MA, Abayomi OA, Olagunju FA, Adesokan FJ.   +5 more
europepmc   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Annals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh, Kyle C. Kern, Nae‐Yuh Wang, Rebecca F. Gottesman, Clinton B. Wright   +4 more
wiley   +1 more source

Programmable scanning diffuse speckle contrast imaging of cerebral blood flow. [PDF]

Neurophotonics
Akbari F, Liu X, Hamedi F, Mohtasebi M, Chen L, Chen L, Yu G.   +6 more
europepmc   +1 more source