Results 101 to 110 of about 345,265 (289)

The cerebral circulation and cerebrovascular disease II: Pathogenesis of cerebrovascular disease

open access: yesBrain Circulation, 2017
In this paper, we review the cerebral circulation and cerebrovascular disease (CVD) with an overview of the major types of CVD pathogenesis. These, as categorized here, are as follows: occlusive injury intrinsic to blood vessels, occlusive injury ...
Ankush Chandra   +4 more
doaj   +1 more source

Vascular Dynamics of Cerebral Gliomas Investigated with Selective Catheter Angiography, Perfusion CT and MRI [PDF]

open access: yes, 2018
Purpose:: To assess if intratumoral blood circulation parameters from dynamic susceptibility contrast (DSC) MRI and dynamic CT deliver comparable results and to compare tumor-related changes in regional cerebral blood flow (rCBF) and regional cerebral ...
El Koussy, Marwan   +8 more
core  

Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance

open access: yesAdvanced Science, EarlyView.
By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam   +6 more
wiley   +1 more source

Calibrating Doppler imaging of preterm intracerebral circulation using a microvessel flow phantom

open access: yesFrontiers in Human Neuroscience, 2015
Introduction. Preterm infants are born during critical stages of brain development, in which the adaptive capacity of the fetus to extra-uterine environment is limited. Inadequate brain perfusion has been directly linked to preterm brain damage. Advanced
Fleur A. Camfferman   +14 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li   +8 more
wiley   +1 more source

Psychoanalysis and neurosciences: fuzzy outlines? Notes on the notion of cerebral plasticity [PDF]

open access: yes, 2017
“Psychoanalysis versus psychiatry” and “unconscious versus brain” are classic oppositions between different perspectives on the human being and mental suffering.
Mantilla, Maria Jimena
core   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

Pharmacoeconomical assessment of сerebrolysin in the treatment of the acute disturbances of cerebral circulation

open access: yesФармакоэкономика, 2015
: the acute disturbances of cerebral circulation incidence accounts for nearly 70-80% of all such diseases in population, while this annual rate in Russian health care is about 2,19 cases on 1000 individuals. Pharmacoeconomic evaluation of this pathology 
A. Yu. Kulikov, L. A. Komarov
doaj  

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