The cerebral circulation and cerebrovascular disease II: Pathogenesis of cerebrovascular disease
In this paper, we review the cerebral circulation and cerebrovascular disease (CVD) with an overview of the major types of CVD pathogenesis. These, as categorized here, are as follows: occlusive injury intrinsic to blood vessels, occlusive injury ...
Ankush Chandra+4 more
doaj +2 more sources
Cerebral Collateral Circulation in the Era of Reperfusion Therapies for Acute Ischemic Stroke
Clinical outcomes of patients with acute ischemic stroke depend in part on the extent of their collateral circulation. A good collateral circulation has also been associated with greater benefit of intravenous thrombolysis and endovascular treatment ...
Simone M. Uniken Venema+4 more
semanticscholar +1 more source
Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow
Astrocytes provide neurons with essential metabolic and structural support, modulate neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to sense conditions of potential metabolic insufficiency. Here we show that
N. Marina+13 more
semanticscholar +1 more source
Comorbidities are a hallmark of stroke that both increase the incidence of stroke and worsen outcome. Hypertension is prevalent in the stroke population and the most important modifiable risk factor for stroke.
M. Cipolla, D. Liebeskind, Siu-Lung Chan
semanticscholar +1 more source
NeoDoppler: New ultrasound technology for continuous cerebral circulation monitoring in neonates
Background There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates.
S. D. Vik+4 more
semanticscholar +1 more source
Impact of Metabolic Diseases on Cerebral Circulation: Structural and Functional Consequences.
Metabolic diseases including obesity, insulin resistance, and diabetes have profound effects on cerebral circulation. These diseases not only affect the architecture of cerebral blood arteries causing adverse remodeling, pathological neovascularization ...
Maha Coucha+4 more
semanticscholar +1 more source
Autoregulation of Cerebral Blood Flow During 3-h Continuous Cardiopulmonary Resuscitation at 27°C
Introduction: Victims of accidental hypothermia in hypothermic cardiac arrest (HCA) may survive with favorable neurologic outcome if early and continuous prehospital cardiopulmonary resuscitation (CPR) is started and continued during evacuation and ...
Sergei Valkov+11 more
doaj +1 more source
Intracranial collateral circulation and its role in neurovascular pathology
Background Collateral circulation is a vascular network which maintains the blood flow after the partial blockage of primary vascular pathways. This acts as potential vascular supplementary system and plays important role in the cerebral ischemia.
Harold E. Vasquez+7 more
doaj +1 more source
Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations
We propose a detailed CellML model of the human cerebral circulation that runs faster than real time on a desktop computer and is designed for use in clinical settings when the speed of response is important.
Shan Su+4 more
semanticscholar +1 more source
H2S mediates the vasodilator effect of endothelin-1 in the cerebral circulation.
H2S is an endogenous gasotransmitter that increases cerebral blood flow. In the cerebral vascular endothelium, H2S is produced by cystathionine δ-lyase (CSE). Endothelin-1 (ET-1) has constrictor and dilator influences on the cerebral circulation.
Shalinkumar Patel+7 more
semanticscholar +1 more source