Results 271 to 280 of about 333,615 (337)

Investigation of the Determinants of Disease Severity in Patients with Idiopathic Normal Pressure Hydrocephalus

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background The determinants of the severity of idiopathic normal pressure hydrocephalus (iNPH) have not been examined previously. Objective To reveal the clinical determinants of the clinical severity of iNPH in detail. To provide some clinical remarks and contributions to the understanding of the pathophysiology.
Halil Onder   +3 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn   +18 more
wiley   +1 more source

Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Inhibition of Nod‐like receptor protein 3 (NLRP3) inflammasome within the central nervous system (CNS) is a promising therapeutic target for the treatment of Parkinson's disease (PD). Objectives This phase 1b open‐label study was conducted in elderly healthy volunteers (HV) and PD patients.
Nicholas Clarke   +11 more
wiley   +1 more source

Protective Roles of Prebiotics and Probiotics Against Environmental Pollutant‐Induced Toxicities: A Systematic Review of Animal Studies

open access: yesMolecular Nutrition &Food Research, EarlyView.
Pollutant‐induced epithelial damage also leads to a cascade of harmful effects, including reduced mucus secretion, decreased luminal pH, and enhanced absorption of toxins. These changes contribute to oxidative stress (↑ malondialdehyde (MDA); ↓ superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and heightened ...
Meysam Zarezadeh Ph.D.   +5 more
wiley   +1 more source

A theoretical interpretation of diffusion weighted and intravoxel incoherent motion imaging for cerebrospinal fluid flow

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose Diffusion‐weighted imaging (DWI) and intravoxel incoherent motion (IVIM) imaging are well‐established approaches for evaluating cerebrospinal fluid (CSF) flow in subarachnoid and perivascular spaces, and have recently been applied to study ventricular CSF flow.
Tomohiro Otani   +4 more
wiley   +1 more source

Combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose To develop a non‐contrast MRI method for the simultaneous acquisition of time‐resolved 3D angiographic, perfusion, and multi‐contrast T1‐weighted structural brain images in a single 6 min acquisition. Methods The proposed combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast (CAPRIA+
Thomas W. Okell   +2 more
wiley   +1 more source

The eflect of dopamine on cerebral circulation and metablosm in man

open access: bronze, 1981
Tsuguo Niimi   +4 more
openalex   +2 more sources

On the structural and practical identifiability of multi‐echo BBB‐ASL tracer kinetic models

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose Tracer kinetic models are used in arterial spin labeling (ASL); however, deciding which model parameters to fix or fit is not always trivial. The identifiability of the resultant system of equations is useful to consider, since it will likely impact parameter uncertainty.
Tabitha J. Manson   +6 more
wiley   +1 more source

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