Results 311 to 320 of about 287,896 (381)

Cerebrovascular reactivity differences in healthy cerebral gray and white matter

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose To quantify the speed and magnitude of cerebrovascular reactivity (CVR) metrics in hemispheric gray and white matter. Methods A standardized isoxic hypercapnic cerebrovascular stimulus was administered using an automated arterial gas targeting system while monitoring blood oxygen–level dependent MRI.
Harrison T. Levine   +6 more
wiley   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

open access: yesNeuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

History of pre‐eclampsia negatively impacts stroke severity postpartum in rats

open access: yesNeuroprotection, EarlyView.
Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf   +4 more
wiley   +1 more source

The eflect of dopamine on cerebral circulation and metablosm in man

open access: bronze, 1981
Tsuguo Niimi   +4 more
openalex   +2 more sources

Sex‐specific white matter alterations in children exposed to high pregestational BMI

open access: yesObesity, EarlyView.
Abstract Objective This study investigated whether exposure to high pregestational BMI (≥ 25 kg/m2) is associated with alterations in white matter microstructure in early childhood, explored sex‐specific effects, and examined associations with cognitive performance. Methods A total of 90 children from the Alberta Pregnancy Outcomes and Nutrition (APrON)
Samson Nivins   +5 more
wiley   +1 more source

Synthesis of Dendritic Oligo‐Glycerol Amphiphiles with Different Hydrophobic Segments to Improve their Performance as Nanocarriers

open access: yesChemistryOpen, EarlyView.
The synthesized dendritic oligoglycerol amphiphiles with different hydrophobic moieties show efficient micelle formation at low concentrations (CMC: 0.3–1.1 mg/mL) and a strong drug loading capacity, especially for Nile red and nimodipine. Long alkyl chains (C12) improve cargo encapsulation and biocompatibility, while release kinetics suggest potential
Pooja Kumari   +9 more
wiley   +1 more source

Progress in Aptamer Research and Future Applications

open access: yesChemistryOpen, EarlyView.
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu   +4 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear   +6 more
wiley   +1 more source

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