Results 71 to 80 of about 345,265 (289)

Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]

open access: yes, 2018
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming   +12 more
core  

Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke [PDF]

open access: yes, 2014
Aims: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia.
Bailey, Emma L.   +8 more
core   +2 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

open access: yesAdvanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng   +9 more
wiley   +1 more source

Cerebral aneurysm treatment: modern neurovascular techniques. [PDF]

open access: yes, 2016
Endovascular treatment of cerebral aneurysm continues to evolve with the development of new technologies. This review provides an overview of the recent major innovations in the neurointerventional space in recent ...
Colby, Geoffrey P   +4 more
core   +2 more sources

Directed Navigation of Magnetotactic Bacteria via Magnetotaxis in a 3D Vasculature‐On‐A‐Chip

open access: yesAdvanced Materials Technologies, EarlyView.
A perfusable vascular network is developed to investigate MTB at the single‐microorganism level. MTB is demonstrated to successfully align and navigate along the magnetic field inside the microvessels. Abstract Magnetotactic bacteria (MTB), inherently motile and self‐powered, are promising biorobotic candidates for targeted anti‐cancer drug delivery ...
Brianna Bradley   +6 more
wiley   +1 more source

Fractal Analysis of Retinal Vessels and their Relationship with Cerebral Microcirculation Pathology – A Narrative Review

open access: yesApplied Medical Informatics, 2020
One of the most reliable in vivo examination methods of human microvasculature is represented by ophthalmoscopy. Due to ophthalmoscopy, retinal circulation can reveal multiple morphological details that can serve as diagnosis biomarkers for retinal ...
Adriana Elena Bulboacă   +1 more
doaj  

The changing landscape of chronic thromboembolic pulmonary hypertension management

open access: yesEuropean Respiratory Review, 2017
For patients with chronic thromboembolic pulmonary hypertension (CTEPH), the current standard of care involves surgical removal of fibro-thrombotic obstructions by pulmonary endarterectomy.
Michael Madani   +2 more
doaj   +1 more source

Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]

open access: yes, 2016
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
core   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

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