Results 81 to 90 of about 333,615 (337)

Fractal Analysis of Retinal Vessels and their Relationship with Cerebral Microcirculation Pathology – A Narrative Review

Applied Medical Informatics, 2020
One of the most reliable in vivo examination methods of human microvasculature is represented by ophthalmoscopy. Due to ophthalmoscopy, retinal circulation can reveal multiple morphological details that can serve as diagnosis biomarkers for retinal ...
Adriana Elena Bulboacă, Paul Mihai BOARESCU   +1 more
doaj  

The changing landscape of chronic thromboembolic pulmonary hypertension management

European Respiratory Review, 2017
For patients with chronic thromboembolic pulmonary hypertension (CTEPH), the current standard of care involves surgical removal of fibro-thrombotic obstructions by pulmonary endarterectomy.
Michael Madani, Takeshi Ogo, Gérald Simonneau   +2 more
doaj   +1 more source

Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke [PDF]

, 2014
Aims: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia.
Bailey, Emma L., Crawford, Wendy, Dominiczak, Anna F., Graham, Delyth, McBride, Martin W., McClure, John D., Smith, Colin, Sudlow, Cathie L.M., Wardlaw, Joanna M.   +8 more
core   +2 more sources

Cationic Peptoids for Systemic In Vivo Cartilage‐Targeting

Advanced Science, EarlyView.
Systemically‐dosed Cy5‐labeled cationic peptoid probe (NlysO)7 (yellow) binds to the cartilage's glycosaminoglycan content in vivo across the entire body of a neonatal mouse imaged by light sheet fluorescence microscopy, revealing fluorescence uptake in generic cartilage as well as the developing and ossifying bones.
Chaonan Zhang, Rongmao Qiu, Yongjie Huang, Yinghua Liu, Kui Huang, Suwen Zhao, Yang Li   +6 more
wiley   +1 more source

Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain

Nature Communications
The functional significance of the morphological and genetic changes that occurred in the brain during evolution is not fully understood. Here we show the relationships between evolutionary changes of the brain and glymphatic circulation.
Narufumi Kameya, Itsuki Sakai, Kengo Saito, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Satoru Okuda, Hiroshi Kawasaki   +7 more
doaj   +1 more source

The selective serotonin reuptake inhibitor paroxetine improves right ventricular systolic function in experimental pulmonary hypertension

Journal of Molecular and Cellular Cardiology Plus
Background: Pulmonary hypertension (PH) often leads to right ventricle (RV) failure, a significant cause of morbidity and mortality. Despite advancements in PH management, progression to RV maladaptation and subsequent failure remain a clinical challenge.
Mark T. Waddingham, Hirotsugu Tsuchimochi, Takashi Sonobe, Vasco Sequeira, Md Junayed Nayeem, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo   +7 more
doaj   +1 more source

The Functional State of the Cerebral Circulation Depending on the Localization of Transition Area in Chest Lead of ECG at Orthostasis

Наука. Инновации. Технологии, 2022
The article is devoted to the study of the functional state of the cerebral circulation at orthostasis in persons of young age with different localization of transition area in chest lead of ECG.
Polina Leonidovna Sevriukova, Galina Erdnevna Nastinova, Laura Andreevna Tovmasian, Polina Leonidovna Sevriukova   +3 more
doaj  

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Unilateral Antegrade Cerebral Perfusion versus Deep Hypothermic Circulatory Arrest during Acute Aortic Dissection Repair: A Single Center Experience

Acta Clinica Croatica, 2022
Introduction: The gold standard of circulation strategy and arterial cannulation during acute aortic dissection is still indisputable. Unilateral/bilateral antegrade cerebral perfusion (UACP/BACP) and deep hypothermic circulatory arrest (HCA) remains a
Mehmet Karaçalılar, Mugisha Kyaruzi
doaj  

Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]

, 2016
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
core   +1 more source