Results 81 to 90 of about 345,265 (289)

Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain

Nature Communications
The functional significance of the morphological and genetic changes that occurred in the brain during evolution is not fully understood. Here we show the relationships between evolutionary changes of the brain and glymphatic circulation.
Narufumi Kameya, Itsuki Sakai, Kengo Saito, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Satoru Okuda, Hiroshi Kawasaki   +7 more
doaj   +1 more source

The selective serotonin reuptake inhibitor paroxetine improves right ventricular systolic function in experimental pulmonary hypertension

Journal of Molecular and Cellular Cardiology Plus
Background: Pulmonary hypertension (PH) often leads to right ventricle (RV) failure, a significant cause of morbidity and mortality. Despite advancements in PH management, progression to RV maladaptation and subsequent failure remain a clinical challenge.
Mark T. Waddingham, Hirotsugu Tsuchimochi, Takashi Sonobe, Vasco Sequeira, Md Junayed Nayeem, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo   +7 more
doaj   +1 more source

The Functional State of the Cerebral Circulation Depending on the Localization of Transition Area in Chest Lead of ECG at Orthostasis

Наука. Инновации. Технологии, 2022
The article is devoted to the study of the functional state of the cerebral circulation at orthostasis in persons of young age with different localization of transition area in chest lead of ECG.
Polina Leonidovna Sevriukova, Galina Erdnevna Nastinova, Laura Andreevna Tovmasian, Polina Leonidovna Sevriukova   +3 more
doaj  

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

Unilateral Antegrade Cerebral Perfusion versus Deep Hypothermic Circulatory Arrest during Acute Aortic Dissection Repair: A Single Center Experience

Acta Clinica Croatica, 2022
Introduction: The gold standard of circulation strategy and arterial cannulation during acute aortic dissection is still indisputable. Unilateral/bilateral antegrade cerebral perfusion (UACP/BACP) and deep hypothermic circulatory arrest (HCA) remains a
Mehmet Karaçalılar, Mugisha Kyaruzi
doaj  

Argon does not affect cerebral circulation or metabolism in male humans [PDF]

, 2017
Objective: Accumulating data have recently underlined argońs neuroprotective potential. However, to the best of our knowledge, no data are available on the cerebrovascular effects of argon (Ar) in humans.
Coburn, M. (Marc), Grüne, F. (Frank), Hoeks, S.E. (Sanne), Kazmaier, S. (Stephan), Stolker, R.J. (Robert), Weyland, A. (Andreas)   +5 more
core   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Functional stability of cerebral circulatory system [PDF]

The functional stability of the cerebral circulation system seems to be based on the active mechanisms and on those stemming from specific of the biophysical structure of the system under study.
Moskalenko, Y. Y.
core   +1 more source

Photoplethysmography for Quantitative Assessment of Sympathetic Nerve Activity (SNA) During Cold Stress [PDF]

, 2019
The differences in the degree of sympathetic nerve activity (SNA) over cutaneous blood vessels, although known to be more prominent in the periphery than the core vasculature, has not been thoroughly investigated quantitatively.
Ainslie, Anderson, Appelhans, Billman, Budidha, Budidha, Budidha, Budidha, Burgess, Busija, Daanen, Deng, Eigsti, Esler, Flavahan, Folk, Gordon, Guild, Hart, Hernandez, Hodges, Kaciuba-Uscilko, Korhonen, Kyriacou, Nitzan, Nitzan, Nitzan, Pagani, Penzel, Ramchandra, Reed, Seravalle, Shelley, Silverthorn, Sinski, Smith, Stocks, Tansey, ter Laan, Thayer, Vallbo, Van Vliet, Venema, Wehrwein   +43 more
core   +2 more sources

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source