Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma +9 more
wiley +1 more source
[Dynamic changes in regional cerebral oxygen saturation variability within the first week after birth and relationship with brain injury type in preterm infants]. [PDF]
Wang X, Chu JB, Lu M, Ji YP, Guo CX.
europepmc +1 more source
ABSTRACT Purpose Cerebrospinal fluid (CSF) flow oscillations have emerged as a potentially important marker related to brain clearance, but their acquisition often relies on specialized imaging MRI sequences. The purpose of this work was to enable quantitative assessment of CSF flow associated with cardiac, respiratory, and low‐frequency cycles using ...
Pontus Söderström +5 more
wiley +1 more source
Comparative Analysis of 5 cmH₂O Versus 10 cmH₂O PEEP on Cerebral Oxygen Saturation in Brain Tumor Surgery: A Randomized Controlled Clinical Study. [PDF]
Şahinkaya HH +7 more
europepmc +1 more source
ABSTRACT Objective To investigate test‐retest reliability, measurement error (standard error of measurement [SEM] and minimum detectable difference [MDD]), and the learning effect of the Modified Shuttle Test (MST) in children with asthma. Methods Multicenter cross‐sectional study including clinically stable children aged 6–12 years with asthma.
Lara Bezerra Radis +9 more
wiley +1 more source
Regional cerebral oxygen saturation during initial mobilization of critically ill patients is associated with clinical outcomes: a prospective observational study. [PDF]
Imai R +5 more
europepmc +1 more source
Respiratory Physiotherapy Techniques in Neonatal Intensive Care Units: A Scoping Review
ABSTRACT Background and Purpose Certain physiological characteristics increase the susceptibility of newborns, particularly preterm infants, to pulmonary collapse. In addition, newborns are prone to the accumulation of airway secretions, which, even in small volumes, can compromise respiratory function.
Nilson Willamy Bastos de Souza Júnior +6 more
wiley +1 more source
The effect of personalized perioperative blood pressure management on intraoperative cerebral oxygen saturation, burst suppression ratio and postoperative neurological outcomes in patients having major non-cardiac surgery: an observational substudy of the IMPROVE-pilot randomized controlled trial. [PDF]
Khader W +9 more
europepmc +1 more source
Cerebral Oxygen Saturation Associates with Changes in Oxygen Transport Parameters during Cardiopulmonary Bypass. [PDF]
Eisner C +3 more
europepmc +1 more source
ABSTRACT Background Glutamate is the main excitatory neurotransmitter in the brain, and extracellular levels of glutamate and glycerol (a breakdown product of cell damage) increase after severe acute brain injury. Previous studies report that increased intracerebral glutamate—measured using cerebral microdialysis (CMD)—is associated with unfavorable ...
Trine Hjorslev Andreasen +7 more
wiley +1 more source

