Results 101 to 110 of about 90,220 (261)

Refining diagnostic boundaries and electroclinical profiles of Lennox–Gastaut syndrome through unsupervised clustering

open access: yesEpilepsia, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.
Emanuele Cerulli Irelli   +12 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges

open access: yesFood Safety and Health, EarlyView.
Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew   +12 more
wiley   +1 more source

Research progress on the effects of epidural electrical stimulation on lower extremity function in patients with spinal cord injury

open access: yesFrontiers in Medicine
Lower extremity motor dysfunction after spinal cord injury (SCI) represents a major determinant of long-term disability and reduced quality of life.
Fei Xie, Chao Bai, Xinping Luan, Jian Xu
doaj   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare   +7 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

Comparison of Cranial Ultrasound and Amplitude‐Integrated Electroencephalography in Predicting Neurodevelopmental Outcomes in Neonates With Hypoxic–Ischemic Encephalopathy: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Ultrasound, EarlyView.
In neonates with hypoxic–ischemic encephalopathy (HIE), adverse neurodevelopmental outcomes (NDO) remain common. Amplitude‐integrated EEG demonstrates strong prognostic value for early prediction, while cranial ultrasound (cUS) provides complementary but less definitive information.
Meirong Shu   +6 more
wiley   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

open access: yesJCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf   +5 more
wiley   +1 more source

Association between ADHD symptoms and device‐measured physical activity and sedentary behavior in childhood: A population‐based twin study

open access: yesJCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) symptoms are associated with adverse health outcomes; this may be partially due to unhealthy lifestyle factors such as low physical activity (PA) and high sedentary behavior (SED). However, this association remains unclear.
Narda Ontiveros   +5 more
wiley   +1 more source

Developing an integrated algorithm to support autism diagnostic decisions: Model performance and statistical fairness

open access: yesJCPP Advances, EarlyView.
Abstract Background Best practices in diagnosing autism spectrum disorder require an expert diagnostician to integrate multiple sources of information, including direct observations, interviews, and rating scales completed by knowledgeable informants.
Aaron J. Kaat   +8 more
wiley   +1 more source

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