Results 41 to 50 of about 438,879 (204)

Time History Gaussian Process Regression for Modeling the Dynamics of Ankle Exoskeleton User Comfort

Advanced Robotics Research, EarlyView.
Exoskeletons need to be comfortable, but the perception of comfort may change over time. This study investigated if short‐term time history directly influences comfort. No previous trials’ input features were predictive of comfort. Including the previous trial's comfort score marginally improved model accuracy compared to a model using only the current
Axl Maberry, Bo Cheng, Anne E. Martin
wiley   +1 more source

A Systematic Review of the Clinimetric Properties of Habitual Physical Activity Measures in Young Children with a Motor Disability

International Journal of Pediatrics, 2012
Aim. To identify and systematically review the clinimetric properties of habitual physical activity (HPA) measures in young children with a motor disability. Method. Five databases were searched for measures of HPA including: children aged
Stina Oftedal, Kristie L. Bell, Louise E. Mitchell, Peter S. W. Davies, Robert S. Ware, Roslyn N. Boyd   +5 more
doaj   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Modeling of Muscle Activation from Electromyography Recordings in Patients with Cerebral Palsy

Applied Sciences, 2018
The present study estimated muscle activation from electromyographic (EMG) recordings in patients with cerebral palsy (CP) during cycling on an ergometer.
Susmita Roy, Ana Alves-Pinto, Renée Lampe   +2 more
doaj   +1 more source

Preserving Motor Features by Alternative Re‐Referencing to Remove Heart Artifact on the Stentrode

Advanced Science, EarlyView.
Endovascular brain‐computer interfaces record neural activity from within cerebrovasculature, at the expense of electrocardiogram contamination. Band‐limited independent component analysis separates this heart‐based artifact from task‐relevant neural activity in each frequency band, enabling the reconstruction of cleaner neural recordings without the ...
Ariel K. Feldman, Kriti Kacker, Rahyun Yun, Nikole Chetty, James Bennett, Peter E. Yoo, Raul G. Nogueira, Jennifer L. Collinger, Nicholas L. Opie, Thomas J. Oxley, David F. Putrino, Douglas J. Weber   +11 more
wiley   +1 more source

Preliminary Effects of a Robot-Based Therapy Program with Atlas-2030 in Children with Cerebral Palsy Receiving Care at a Specialized Rehabilitation Center

Applied Sciences
Robot-based rehabilitation emerges as a promise to enhance mobility and improve the rehabilitation outcomes in children with cerebral palsy. The study aimed to evaluate the preliminary effects of a robot-based therapy program with Atlas-2030 on ...
Igor Salinas-Sánchez, María R. Huerta-Teutli, David Cordero-Cuevas, Guadalupe Maldonado-Guerrero, Raide A. González-Carbonell   +4 more
doaj   +1 more source

Indigenous health equity in health register ascertainment and data quality: a narrative review

International Journal for Equity in Health, 2022
Background Health registers play an important role in monitoring distribution of disease and quality of care; however, benefit is limited if ascertainment (i.e., the process of finding and recruiting people on to a register) and data quality (i.e., the ...
Karen Wright, Rachel M. Tapera, N. Susan Stott, Alexandra Sorhage, Anna Mackey, Sîan A. Williams   +5 more
doaj   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Bridging the gap: reflections on co-creation in knowledge translation

Research Involvement and Engagement
Background To address the research-practice gap, knowledge translation is a crucial step in which co-creation, including patient and public involvement (PPI), is key.
Marjolijn Ketelaar, Maureen Bult, Marike Willems-op Het Veld, Karen van Meeteren, Marij Roebroeck, Jeanine Voorman   +5 more
doaj   +1 more source