Results 101 to 110 of about 137,378 (339)
Cerebral vasoreactivity in response to a headof-bed position change is altered in patients with moderate and severe obstructive sleep apnea [PDF]
, 2018 Obstructive sleep apnea (OSA) can impair cerebral vasoreactivity and is associated with an increased risk of cerebrovascular disease. Unfortunately, an easy-to-use, non-invasive, portable monitor of cerebral vasoreactivity does not exist. Therefore, we
Blanco, Igor +9 more
core +4 more sources
Advanced Science, EarlyView.Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu +13 more
wiley +1 more source
Intracranial mechanisms for preserving brain blood flow in health and disease [PDF]
, 2017 The brain is an exceptionally energetically demanding organ with little metabolic reserve, and multiple systems operate to protect and preserve the brain blood supply. But how does the brain sense its own perfusion?
Malpas, Simon C +2 more
core +2 more sources
Advanced Science, EarlyView.A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei +13 more
wiley +1 more source
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Cerebrovascular events primary prevention in metabolic syndrome patients
Кардиоваскулярная терапия и профилактика, 2006 Aim. To study effects of therapy with bisoprolol (Concor®) and deproteinized hemoderivate (Actovegin®) on circadian blood pressure profile (CBPP), carbohydrate, lipid metabolism, and cerebral perfusion in patients with metabolic syndrome (MS) and mild ...
V. B. Mychka +4 more
doaj
Biomedicine HubIntroduction: In acute ischaemic stroke, the key treatment to reduce infarct growth is reperfusion, achieved through thrombolysis, endovascular thrombectomy, or endogenous reperfusion.
Rudy Goh +7 more
doaj +1 more source
Characterization of the microvascular cerebral blood flow response to obstructive apneic events during night sleep [PDF]
, 2018 Peer ReviewedPostprint (author's final ...
Blanco, Igor +4 more
core +2 more sources
Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance
Advanced Science, EarlyView.By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam +6 more
wiley +1 more source
Advanced Science, EarlyView.A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li +8 more
wiley +1 more source