Results 121 to 130 of about 137,378 (339)

Defining metabolic abnormalities in acute human traumatic brain injury with cerebral microdialysis and multimodality monitoring.

PLoS ONE
ObjectiveWe aimed to compare the prevalence and multimodal associations of mitochondrial dysfunction as defined by published cerebral-microdialysis-based criteria versus our novel multimodality-monitoring-based criteria in acute traumatic brain injury ...
Michael S Baker, Sara Venturini, Caroline Lindblad, Joshua M Heihre, Ivan Timofeev, Mathew R Guilfoyle, Peter J Hutchinson, Keri L H Carpenter, Adel Helmy   +8 more
doaj   +1 more source

No Influence of Ovarian Hormones on Cerebrovascular Responses to the Valsalva Maneuver [PDF]

, 2010
Cerebral blood flow is modulated in part by arterial perfusion pressure and autonomic neural activity. Valsalva straining drives increases in cerebral perfusion pressure that may challenge cerebrovascular regulatory mechanisms.
Barrera, Chelsea R, Cooke, William H, Lara (Undergraduate), Jesus I, Martinez, Ashley, Moralez, Gilbert   +4 more
core   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Study on in Vivo Pial Vessels Alterations and Activity of Isolated Vascular Smooth Muscles in Abdominal Hypertension Rats

Folia Medica, 2019
Background: Intra-abdominal hypertension is known as a factor affecting cerebral haemodynamics. Sustainably elevated abdominal pressure may disturb the balance of intracranial/blood pressure ratio, eventually developing perfusion pressure to drop.
Turiyski Valentin I., Vassilev Petar G., Ardasheva Raina G., Dobrev Hristo P., Kristev Athanas D.   +4 more
doaj   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Relationship between brain tissue oxygen (PbrO2) and cerebral perfusion pressure (CPP) [PDF]

, 1997
Paolo Bruzzone, G Bellinzona, Roberto Imberti, L Carnevale, S Noli, Maurizio Raimondi, Paolo Bianchi, RV Dionigi   +7 more
openalex   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Cerebral hypoperfusion resulting from improper cannulation positioning during aortic dissection surgery: a case report

Journal of Cardiothoracic Surgery
Background Selective antegrade cerebral perfusion (sACP) is a crucial cerebral protection technique employed during aortic dissection surgeries involving cardiopulmonary bypass.
Qingping Xia, Fei Lin, Yong Cao, Li Deng
doaj   +1 more source

Cerebrovascular Hemodynamics during Concentric and Eccentric Phases of Heavy Resistance Exercise [PDF]

, 2013
Rapid and drastic fluctuations in arterial blood pressures, such as those occurring during heavy resistance exercise pose a unique challenge to the maintenance of cerebral perfusion. During high-intensity leg cycling, regulation of cerebral perfusion is
Cooke, William H, Moralez, Gilbert, Raven, Peter B, Rickards, Caroline A, Romero, Steven A.   +4 more
core   +1 more source

Preliminary experience of the estimation of cerebral perfusion pressure using transcranial Doppler ultrasonography [PDF]

, 2001
Eric Schmidt
openalex   +1 more source