Results 271 to 280 of about 137,378 (339)

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

Experimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley, Tomoki Watada, Go Ito, Ai Shimada, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Tadayoshi Miyamoto   +7 more
wiley   +1 more source

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

Experimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster, Travis Dylan Gibbons, Hannah Grace Caldwell, Connor A. Howe, Jennifer S. Duffy, Andrew R. Steele, Justin A. Monteleone, Jay M. J. R. Carr, Jodie Lauren Koep, Tenasia D. R. Monaghan, David B. MacLeod, Philip N. Ainslie   +11 more
wiley   +1 more source

Cerebral haemodynamic responses to inspiratory muscle work

Experimental Physiology, EarlyView.
Abstract Fatiguing inspiratory work has been shown to evoke a sympathetically mediated reflex that has systemic cardiovascular consequences, including increases in heart rate and blood pressure and a decrease in resting limb vascular conductance. Moreover, the response to this reflex appears to be attenuated in females compared with males.
Andrew H. Ramsook, Morgan A. Hughes, Wyatt W. Pruter, Kevin L. Webb, Ali Ataie, Chad C. Wiggins, Gabrielle A. Dillon, Sarah E. Baker, Michael J. Joyner   +8 more
wiley   +1 more source

No difference in mean middle cerebral artery blood velocity responses between lower‐ and upper‐body unilateral resistance exercise in untrained individuals

Experimental Physiology, EarlyView.
Abstract Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure that are mirrored by middle cerebral artery blood velocity (MCAv). However, whether lower‐ or upper‐body RE elicits a differential cerebrovascular response has not yet been examined.
Stephanie Korad, Toby Mündel, Blake G. Perry   +2 more
wiley   +1 more source

Changes of the Vital Sign, Cerebral Perfusion Pressure and Intracranial Pressure in Variable Degree of Head Elevation.

, 1989
Chi Yc, Bae Jh, Han Dr, Doh Es, Kim Ol, Choi By, S H Cho   +6 more
openalex   +1 more source

Exploring the nexus: Clinical and physiological correlation between cardiovascular disease and colorectal cancer

Experimental Physiology, EarlyView.
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir, Ali Murtada, Matti Jubouri, Wael Awad, Ian Williams, Damian M. Bailey   +5 more
wiley   +1 more source

Optimizing the predictive validity of NIRS kinetic profiles to predict aerobic capacity from a resting skeletal muscle occlusion test

Experimental Physiology, EarlyView.
Abstract Measuring and monitoring individual cardiorespiratory fitness through a valid and accessible non‐exhaustive surrogate is required. Techniques measuring haemodynamics have shown promise, and this study aimed to optimize the predictive validity of these approaches alongside developing predictive equations.
Heru Syarli Lesmana, Kyohei Marume, Justin S. Lawley   +2 more
wiley   +1 more source

The clinical and physiological profiles of kissing stents in endovascular reconstruction of aortoiliac occlusive disease

Experimental Physiology, EarlyView.
Abstract Aortoiliac occlusive disease affecting the abdominal aorta and iliac arteries is conventionally treated with open surgical repair and is the mainstay of treatment. Endovascular techniques have become a less invasive alternative, especially for high‐risk patients.
Christopher J. Goulden, Matti Jubouri, Eka Narayan, Sakshi Roy, Fatima Kayali, Wael I. Awad, Damian M. Bailey, Ian M. Williams, Mohamad Bashir   +8 more
wiley   +1 more source

Sex differences in cerebral blood flow and cardiac function in response to exercise in the heat

Experimental Physiology, EarlyView.
Abstract We investigated the effect of exercising in hot conditions on cerebral blood flow and systolic left ventricular (LV) function in males and females, to explore sex differences. The experimental condition consisted of walking on a treadmill at 5 km/h and 2% incline, inside a heat chamber at 40°C (50% relative humidity), for 90 min.
João Carlos Locatelli, Juliene G. Costa, Kristanti W. Wigati, Jesse L. Criddle, Julie J. Collis, Xingwei Xu, Louise H. Naylor, Howard H. Carter, Shane K. Maloney, Robert A. McLaughlin, Andrew Haynes, Helen Jones, Keith George, Daniel J. Green   +13 more
wiley   +1 more source