Evaluation of Cerebral Perfusion Pressure, Cerebral Blood Flow, and Cerebral Oxygenation at Different Head of Bed Positions Using Transcranial Doppler and Near-Infrared Spectroscopy in Postoperative Neurosurgical Patients. [PDF]
Baskar N +6 more
europepmc +1 more source
The role of orexin A in the pathogenesis of ischaemic stroke at high altitude
Schematic illustration of the experimental design. This study investigated the role of Orexin A in the pathogenesis of ischemic stroke at high altitude. Abstract Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression.
Minxia Zhu +7 more
wiley +1 more source
Evaluating the Status of the Injured Brain: Cerebrovascular Reserve (CVR) Is Not Equivalent to Induced Cerebrovascular Reactivity (iCVRx) and Induced Pressure Reactivity (iPRx) in Defining the Critical Cerebral Perfusion Pressure (CPP). [PDF]
Nemoto EM, Bragin DE, Yonas H.
europepmc +1 more source
Abstract The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time‐corrected ratio calculated on MCAv and MAP changes induced by repeated squat–stands (RSS) at 0.05 and 0.10 Hz ...
Lawrence Labrecque +6 more
wiley +1 more source
Effects of positive end-expiratory pressure on intracranial pressure, cerebral perfusion pressure, and brain oxygenation in acute brain injury: Friend or foe? A scoping review. [PDF]
Zunino G, Battaglini D, Godoy DA.
europepmc +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage +10 more
wiley +1 more source

