Blood pressure variability is an emerging risk factor for stroke, cognitive impairment, and dementia, possibly through links with cerebral hypoperfusion.
Isabel J. Sible +14 more
doaj +1 more source
Cerebral Perfusion Pressure Directed-Therapy Modulates Cardiac Dysfunction After Traumatic Brain Injury to Influence Cerebral Autoregulation in Pigs. [PDF]
Armstead WM, Vavilala MS.
europepmc +3 more sources
Head Elevation, Cerebral Venous System, and Intracranial Pressure: Review and Hypothesis
Background Facilitation of venous outflow from the brain is largely believed to be responsible for the beneficial effect of head elevation on intracranial pressure (ICP). However, the impact on cerebral perfusion pressure can be deleterious. Although the
Mithun G. Sattur +4 more
doaj +1 more source
The brain's ability to maintain cerebral blood flow approximately constant despite cerebral perfusion pressure changes is known as cerebral autoregulation (CA) and is governed by vasoconstriction and vasodilation.
Alexander Ruesch +5 more
doaj +1 more source
Cerebral perfusion is determined by segmental perfusion pressure for the intracranial compartment (SPP), which is lower than cerebral perfusion pressure (CPP) because of extracranial stenosis. We used the Thevenin model of Starling resistors to represent
Mindaugas Pranevicius +2 more
doaj +1 more source
Optimal Cerebral Perfusion Pressure: Targeted Treatment for Severe Traumatic Brain Injury
Identification of individual therapy targets is critical for traumatic brain injury (TBI) patients. Clinical outcomes depend on cerebrovascular autoregulation (CA) impairment.
V. Petkus +10 more
semanticscholar +1 more source
Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core +1 more source
Early cerebral perfusion pressure augmentation with phenylephrine after traumatic brain injury may be neuroprotective in a pediatric swine model* [PDF]
Objective: Cerebral perfusion pressureage, and current guidelines recommend maintaining cerebral perfusion pressure between 40 mm Hg–60 mm Hg. Although adult traumatic brain injury studies have observed an increased risk of complications associated with ...
Adelson +31 more
core +2 more sources
A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M +5 more
core +5 more sources
Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury: a CENTER-TBI study. [PDF]
Riemann L +9 more
europepmc +3 more sources

