Results 31 to 40 of about 259,881 (379)

Análise da capacidade reactiva da circulação intracerebral pelo efeito do CO2. Um método de fácil execução.

Acta Médica Portuguesa, 1998
Maintenance of cerebral perfusion pressure is a prerequisite for the prevention of cerebral ischaemia. Physiological fluctuations in systemic perfusion pressure are compensated by cerebrovascular autoregulation.
A Baptista, J Ribeiro
doaj   +1 more source

Intrathoracic pressure regulation therapy applied to ventilated patients for treatment of compromised cerebral perfusion from brain injury

Journal of Medical Case Reports, 2018
Background Reducing intrathoracic pressure in the setting of compromised cerebral perfusion due to acute brain injury has been associated with reduced intracranial pressure and enhanced cerebral perfusion pressure and blood flow in animals.
Anja K. Metzger, Nicolas Segal, Dai Wai Olson, Stephen A. Figueroa, Farid G. Sadaka, Catherine A. Krause, James R. Homuth, Nathaniel T. Burkhart, Robert T. Neumann, Keith G. Lurie, Victor A. Convertino   +10 more
doaj   +1 more source

Effect of Standard vs Intensive Blood Pressure Control on Cerebral Blood Flow in Small Vessel Disease The PRESERVE Randomized Clinical Trial [PDF]

, 2018
Importance: Blood pressure lowering is considered neuroprotective in patients with cerebral small vessel disease, however more “intensive” regimens may increase cerebral hypoperfusion. We examined the effect of intensive vs.
Barrick, TR, Blamire, AM, Cambridge, VC, Croall, ID, Ford, GA, Khan, U, Markus, HS, Morris, RG, Moynihan, B, O'Brien, JT, PRESERVE Study Team, Tozer, DJ   +11 more
core   +1 more source

Feasibility of individualised severe traumatic brain injury management using an automated assessment of optimal cerebral perfusion pressure: the COGiTATE phase II study protocol

BMJ Open, 2019
Introduction Individualising therapy is an important challenge for intensive care of patients with severe traumatic brain injury (TBI). Targeting a cerebral perfusion pressure (CPP) tailored to optimise cerebrovascular autoregulation has been suggested ...
E. Beqiri, P. Smielewski, C. Robba, M. Czosnyka, M. Cabeleira, J. Tas, J. Donnelly, J. Outtrim, P. Hutchinson, D. Menon, G. Meyfroidt, B. Depreitere, M. Aries, A. Ercole   +13 more
semanticscholar   +1 more source

Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]

, 2004
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C., Harazny, J., Hilgers, K.F., Michelson, G., Oehmer, S., Schmieder, R.E.   +5 more
core   +1 more source

PTPRG is an ischemia risk locus essential for HCO3–-dependent regulation of endothelial function and tissue perfusion

eLife, 2020
Acid-base conditions modify artery tone and tissue perfusion but the involved vascular-sensing mechanisms and disease consequences remain unclear. We experimentally investigated transgenic mice and performed genetic studies in a UK-based human cohort. We
Kristoffer B Hansen, Christian Staehr, Palle D Rohde, Casper Homilius, Sukhan Kim, Mette Nyegaard, Vladimir V Matchkov, Ebbe Boedtkjer   +7 more
doaj   +1 more source

Is High Blood Pressure Self-Protection for the Brain? [PDF]

, 2016
Rationale: Data from animal models of hypertension indicate that high blood pressure may develop as a vital mechanism to maintain adequate blood flow to the brain.
Adams, Zoe H, Burchell, Amy E, Harris, Ashley D, Hart, Emma C, Manghat, Nathan E, Neumann, Sandra, Nightingale, Angus K, Paton, Julian F, Ratcliffe, Laura E, Rodrigues, Jonathan C, Warnert, Esther Ah, Wise, Richard G   +11 more
core   +2 more sources

Transcranial Doppler Ultrasound, a Review for the Pediatric Intensivist

Children, 2022
The use of transcranial Doppler ultrasound (TCD) is increasing in frequency in the pediatric intensive care unit. This review highlights some of the pertinent TCD applications for the pediatric intensivist, including evaluation of cerebral hemodynamics ...
Marlina Elizabeth Lovett, Nicole F. O’Brien   +1 more
doaj   +1 more source

Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]

, 1967
As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Edamatsu, Kazuyasu, Morimitsu, Junsuke, Nakashima, Yoshihiko, Okumura, Nikichi, Otsuki, Saburo, Watanabe, Shosuke   +5 more
core   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon, Celestine Santosh, Christopher McCabe, Craig A Robertson, I Mhairi Macrae, Keith W Muir, Kucinski T, Lindsay Gallagher, Maria del Rosario Lopez-Gonzalez, William M Holmes   +9 more
core   +1 more source